Zhongshan Latterson Biotechnology Co., Limitado.

Otros productos de venta caliente (Polvo crudo)

» Otros productos de venta caliente (Polvo crudo)

  • CASO 78755-81-4 Pharmaceutical Raw Materials Flumazenil For Nootropic Supplement

    CATEGORÍA Y ETIQUETAS:
    Otros productos de venta caliente (Polvo crudo)
    Número de modelo : CASO: 78755-81-4
    Certificación : GMP,SGS,ISO 9001:2008,COMESTIBLE SEGÚN LA LEY JUDÍA
    Lugar de origen : porcelana
    MOQ : 10gramo
    Precio : Negociable
    Términos de pago : Western Union, MoneyGram, Transferencia bancaria, Bitcoin
    Capacidad de suministro : 3000kg/mes
    El tiempo de entrega : Usually within 7 dias laborables
    detalles del empaque : Stealth and discreet packaging
    nombre del producto : Flumazenil
    CASO : 78755-81-4
    MF : C15H14FN3O3
    MW : 303.29
    Pureza : 99.0%
    apariencia : Polvo blanco
    consulta
    • Especificaciones

    CASO 78755-81-4 Pharmaceutical Raw Materials Flumazenil For Nootropic Supplement

    Superioridad

    Zhongshan Latterson Biotechnology Co., Limitado., es una empresa farmacéutica integral, que se especializó en tecnología biofarmacéutica sobre 7 años. La empresa está ubicada en la ciudad de Zhongshan, Provincia de Guangdong , porcelana.
    Nuestra fábrica cubre un área de 33500 metros cuadrados, con un ambiente limpio y un diseño agradable. Hay varios talleres grandes o medianos y un centro de investigación y control de calidad con equipos avanzados.. En el presente, Nuestros principales productos son la serie de esteroides anabólicos., Serie de péptidos, Serie de anestésicos locales. Nuestros productos alcanzan el estándar avanzado del mercado nacional., muchos de los cuales alcanzan el estándar internacional, los certificados contienen: COMESTIBLE SEGÚN LA LEY JUDÍA , YO ASI 9001:2008 , GMP , SGS.

    nombre del producto Flumazenil
    As Romazicon
    Sinónimos Ethyl 8-fluoro-5-methyl-6-oxo-5, 6-dihydro-4h-imidazo[1, 5-a][1, 4]benzodiazepine-3-carboxylate; FLUMAZENIL; 8-FLUORO-5, 6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1, 5-A][1, 4]BENZO-DIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER; 8-FLUORO-5, 6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1, 5-A][1, 4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL EST; 4H-IMIDAZO[1, 5-A][1, 4]BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5, 6-DIHYDRO-5-METHYL-6-OXO-, ETHYL ESTER; RO 15-1788; Flumazenil, Flumazepil; FlumazenilUsDmf
    CASO 78755-81-4
    Pureza 99.0%
    Calificación As
    Brand Name STEROID
    MF. C15H14FN3O3
    MW. 303.29
    Apariencia White power
    Categorías Active Pharmaceutical Ingredients; GABA/Glycine receptor; GABA; Amines; heterociclos; intermedios & Productos químicos finos; Productos farmacéuticos; ZEBETA; Other APIs; Antagonist; API
    Propiedades Colourless crystals
    Almacenamiento Original package at cool dark place

    Fumazenil is an imidazobenzodiazepine derivative.

    Fumazenil a potent benzodiazepine receptor antagonist.

    Descripción:

    Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective receptor antagonist primarily available by injection only, and the only GABAA negative allosteric modulator on the market today. It has antagonistic and antidote properties , through competitive inhibition. It was first introduced in 1987 by Hoffmann-La Roche under the trade name Anexate, but only approved by the FDA on December 20, 1991. Flumazenil went off patent in 2008, so at present generic formulations of this drug are available. Intravenous flumazenil is primarily used to treat overdoses and to help reverse anesthesia. Administration of flumazenil by sublingual lozenge and topical cream has also been tested.

    Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system. Reversing drowsiness, sedation, and other effects caused by benzodiazepine Flumazenil is a benzodiazepine antagonist. It works by blocking receptors in the brain and central nervous system that benzodiazepine need to reach to be active, which helps reduce drowsiness and sedation.

    Aplicaciones:

    Flumazenil is of benefit in patients who become excessively drowsy after benzodiazepines are used for either diagnostic or therapeutic procedures. It has been used as an antidote in the treatment of benzodiazepine overdoses.It reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABAA receptor. There are many complications that must be taken into consideration when used in the acute care setting.These include lowered seizure threshold, agitation, and anxiousness. Flumazenil’s short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms.

    It is also sometimes used to reverse the effects of benzodiazepines after surgery in a manner similar to naloxone’s application to reverse the effect of opiates and opioid following surgery. This requires careful monitoring by an anesthesiologist due to potential side effects and serious risks associated with both over-administering flumazenil and the removal of patient life-support and monitoring equipment before the benzodiazepines have worn off (due to flumazenil masking their continued effect).

    Flumazenil has been effectively used to treat overdoses of non-benzodiazepine hypnotics, such as zol-pidem,. It may also be effective in reducing excessive daytime sleepiness while improving vigilance in primary hypersomnias, such as idiopathic hypersomnia. It has also been used in hepatic encephalopathy, though results have been mixed. The onset of action is rapid and usually effects are seen within one to two minutes. The peak effect is seen at six to ten minutes. The recommended dose for adults is 200 μg every 1-2 minutes until the effect is seen, to a maximum of 3 mg per hour. It is available as a clear, colourless solution for intravenous injection, que contiene 500 μg in 5 ml.

    Half life:

    Initial distribution half-life is 4 a 11 minutes and the terminal half-life is 40 a 80 minutos. Prolongation of the half-life to 1.3 hours in patients with moderate hepatic impairment and 2.4 hours in severely impaired patients. Compared to adults, the elimination half-life in pediatric patients was more variable, averaging 40 minutos (range: 20 a 75 minutos).

    Benefits and Effects:

    Flumazenil is of benefit in patients who become excessively drowsy after benzodiazepine are used for either diagnostic or therapeutic procedures. It has been used as an antidote in the treatment of benzodiazepine overdoses. There are many complications that must be taken into consideration when used in the acute care setting.These include lowered seizure threshold, agitation, and anxiousness. Flumazenil’s short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms. Flumazenil has been effectively used to treat overdoses of non-benzodiazepine hypnotics, such as zolpidem, zaleplon and zopiclone.

    COA:

    Elementos de análisis Especificación Resultados
    Apariencia Polvo cristalino blanco Polvo cristalino blanco
    Identificación The sample’s IR spectrum is according with spectrum of Flumazenil,The retention time of the major peak Flumazenil in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation Cumple
    Punto de fusion 198ºC to 202ºC 200.6ºC to 200.9ºC
    Appearance of solution The solution is clear and is not Intenser than reference solution BY7 Cumple
    Impurity C NMT 0.2% 0.02%
    Impurity A NMT 0.10% No detectado
    Impurity B NMT 0.2% 0.03%
    Impurity D NMT 0.10% 0.03%
    Impurity E NMT 0.10% No detectado
    Impurity F NMT 0.10% No detectado
    Individual unknown impurituy NMT 0.10% 0.02%
    Total impurities NMT 0.5% 0.1%
    Pérdida por secado NMT 0.5% 0.2%
    Sulphated ash NMT 0.1% 0.05%
    Metales pesados ≤0.5 ppm 5ppm
    Microbial limits
    (for Injection)
    Bacteria not more than 50CFU/g <10 CFU/g
    Microbial limits Mildew and microzyme not more than 50CFU/g <10 CFU/g
    Microbial limits Escherichia coli absence Absence
    Etanol NMT2000ppm No detectado
    Chloroform NMT30ppm No detectado
    Acetic acid NMT4000ppm No detectado
    diclorometano NMT600ppm <0.002%
    Ethyl ethanoate NMT5000ppm <0.003%
    DMF NMT750ppm No detectado
    Ensayo (On dried substance) 98.0-102.0% 99.80%
    Bacterial endotoxins no más que 25.0 USP Endotoxin Units per mg of flumazenil. no más que 8.0 USP Endotoxin Units per mg of flumazenil.
    Guarantees the nature time 36 meses 36 meses

    Nuestro servicio

    1.100% La política de reenvío es nuestro negocio básico. Reenvío del 100% inmediatamente si su paquete permanece en Aduana por 4 días y no se actualiza.
    2.Reembolso total por 15 días de insatisfacción con la calidad.
    3.Podemos proporcionar muestras gratis..
    4.Tenemos un embalaje especial ,Se puede pasar fácilmente por la aduana.Será más seguro..
    5.Nuestra empresa tiene una cooperación a largo plazo con DHL.EMS.Fedex y así sucesivamente. Se puede enviar a su mano más rápidamente. La foto del paquete debe ofrecerse dentro de las 12 horas posteriores a la recepción de su pago de esteroides.
    6.Si tienes la oportunidad de venir a China. Puedo mostrarte nuestro laboratorio.
    7.Nuestra empresa tiene WU, MG, TT, y formas de pago de Bitcoin por adelantado. 95% por el costo de los péptidos al principio por pedido, el resto nos lo puede ofrecer en su próximo pedido;

    Otros productos de venta caliente (Polvo crudo)
    TUDCA (Ácido tauroursodesoxicólico)
    GBL (Y-butirolactona)
    1,4-Butanodiol
    minoxidil
    melatonina
    tretinoína
    Sunifiram
    Pregabalina
    fenacetina
    Paracetamol
    Levamisol HCL
    Pirfenidona
    Epinefrina HCL
    pregnenolona
    Bromhidrato de dextrometorfano monohidrato
    argirelina
    SNAP-8 1 mg/vial
    Teofilina
    Diclofenaco sódico
    Sal sódica de tianeptina
    Noopept
    Mononucleótido de beta-nicotinamida
    propionato de clobetasol
    polietilenglicol(CLAVIJA)
    ketoprofeno
    1,3-clorhidrato de dimetilbutilamina
    polivinilpirrolidona
    baricitinib
    diprofilina
    aminofilina
    tianeptina
    Sulfato De Tianeptina Sulfato

    Formulario de Consulta ( nos pondremos en contacto con usted lo antes posible )

    Nombre:
    *
    Correo electrónico:
    *
    Mensaje:

    Verificación:
    1 + 5 = ?

    Quizás te guste también

  • Cómo hacer un pedido?

    Elige los artículos que quieras;
    Contácteme a través del correo electrónico con su demanda;
    Se reenviará la cotización;
    Hacer el pago;
    Paquete arreglado;
    Envío arreglado.
    Se proporcionará servicio de rastreo.

  • Nuestros productos

    Polvo de esteroides crudos

    SARMS

    Péptidos

    Disolventes

    APIS

    Máquina de filtrado

    Prensa de tabletas

    Viales, caucho, tapas, cripmer

  • Envío de vajilla

    EMS

    DHL

    Fedex

    TNT

    UPS

    EUB / ETK ect.

  • Contáctenos

    Correo electrónico:rawsteroidsale@gmail.com
    ¿Qué es la aplicación?:+8618676137192
    skype : +8618676137192
    Sitio web:http://www.powerfulsteroids.com/