Ketoprofen Pharmaceutical Raw Materials CAS 22071-15-4

Ketoprofen Pharmaceutical Raw Materials CAS 22071-15-4

Ketoprofen Basic information:
Имя: Кетопрофен
КЕЙС: 22071-15-4
MF: C16H14O3
МВт: 254.28
Стандарт: USP
Чистота: Фармацевтический класс 99%
Появление: Эстрадиола 17-гептаноат
chemical properties: Белое кристаллическое твердое вещество
Упаковка: 25поскольку тело борется с изменениями с желанием сохранить накопленный жир из-за своей природы выживания, мышечная ткань часто приносится в жертву, чтобы удовлетворить свои потребности в энергии. / Fiber drum
Uses Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Uses Anti-inflammatory; обезболивающее

Pharmacodynamics

Ketoprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. Ketoprofen has pharmacologic actions similar to those of other prototypical NSAIDs, which inhibit prostaglandin synthesis. Ketoprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and alleviate moderate pain.

Механизм действия

The anti-inflammatory effects of ketoprofen are believed to be due to inhibition cylooxygenase-2 (ЦОГ-2), an enzyme involved in prostaglandin synthesis via the arachidonic acid pathway. This results in decreased levels of prostaglandins that mediate pain, fever and inflammation. Ketoprofen is a non-specific cyclooxygenase inhibitor and inhibition of COX-1 is thought to confer some of its side effects, such as GI upset and ulceration. Ketoprofen is thought to have anti-bradykinin activity, as well as lysosomal membrane-stabilizing action. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation.

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