Raw Steroid Powder Ethinylestradiol / Ethynyl Estradiol CAS 57-63-6 For Treatment Of Female Hypogonadism
Quick Deails
| Nom du produit |
Ethinylestradiol |
| n ° CAS. |
57-63-6 |
| Nom chimique |
NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL |
| Masse moléculaire |
296.41 |
| Formule moléculaire |
C20H24O2 |
| Pureté |
99% |
| Usage |
A synthetic steroid with high oral estrogenic potency |
| Standard |
USP28 |
| Apparence |
White or almost white crystalline powder |
| Forfait |
1kg/aluminium foil bag or as your request |
| Paiement |
T/T,Western union,Bitcoin,Gramme d'argent,ect. |
| Livraison |
After payment 3-7days |
Abstrait
Ethinyl Estradiol is absorbed in the small intestine and reaches a serum peak about 2 hours later. It undergoes extensive metabolism in the liver involving the cytochrome P450 3A4 isoenzyme.
Ethinyl Estradiol and its metabolites are excreted with the bile. Due to the effect of entero hepatic circulation a second peak is seen several hours later. Individually, wide variations exist in the overall absorption process, and can be further modified by drugs that affect the enterohepatic circulation or liver enzymes.
In circulation Ethinyl Estradiol is almost fully bound to plasma albumin. It is metabolized by hydroxylation of the aromatic ring and excreted in both feces and urine, in part as glucuronide and sulfate conjugate.
Ethinyl Estradiol is hormonally effective by activating the estrogen receptor and thus is an estrogen. It finds its most common use in the estrogen-progestin combination preparations of oral contraceptives. Over time, formulations have decreased the Ethinyl Estradiol dose from as high as 100 μg to as low as 10 μg in
spécification
| Article |
spécification |
Résultats |
| Apparence |
White to creamy white, inodore, poudre cristalline. |
poudre cristalline blanche |
| Solubilité |
Insoluble in water; soluble in alcohol, dans le chloroforme, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides. |
Conforme |
| Identification |
UN:IR B:UV |
Conforme |
| Une rotation optique spécifique |
-28°~ -29.5° |
-28.3° |
| Melting range |
180~186ºC |
182.5~185.3ºC |
| Perte au séchage |
≤1.0% |
0.45% |
| Residual Solvents |
Acetone≤0.5% |
0.08% |
| Essai |
97.0~102.0% (on the dried basis) |
99.43% |
| Particle Size |
90% ≤10μ |
Conforme |
| Conclusion |
The product complies with specification in USP34 |
Application
As Estinyl, EE2 was formerly used for hormone replacement therapy in menopause and the treatment of femalehypogonadism, loss of menstruation, dysmenorrhea, acné, prostate cancer, et cancer du sein. Cependant, in more recent times, EE2 is mainly used in COCs. In contraception, due to concerns of unopposed estrogen action and the possible increased risk of endometrial cancer that accompanies this, EE2 is formulated in combination with progestins. EE2 is little used in menopausal hormone replacement therapy.
EE2 has been used at very high dosages (1-2 mg/jour) in the treatment of prostate cancer.
Related Female Hormone Steroids
| Estradiol |
Estrone |
Hydrocortisone |
| Valérate d'estradiol |
Estriol |
Hydrocortisone acetate |
| Estradiol benzoate |
Nylestriol |
|
| Estradiol cypionate |
Diethylstilbestrol |
Prednisone acetate |
| Estradiol enantate |
HEXESTROL |
Bentelan |
| Ethynyl estradiol |
Progesterone |
Betamethasone |
| Algestone acetophenide |
Medroxyprogesterone acetate |
Clobetasol propionate |
| Ethisterone |
Norethindrone |
Halobetasol propionate |
| 19-Norethindrone acetate |
Mifepristone |
Deflazacort |
| Norethisterone Enanthate |
Methyldienedione |
Tazarotene |
| Ethynodiol diacetate |
Eplerenone |
Ecdysone |
| Pregnenolone acetate |
Levonorgestrel |
Desloratadine |
| Lynestrenol |
Allylestrenol |
Prednisolone phosphate sodium |
| Chlormadinone acetate |
Dienogestrel |
Fluorometholone Acetate |
| Cyproterone acetate |
Drospirenone |
Dexamethasone Acetate |
| Megestrol acetate |
Prégnénolone |
Dexamethasone Sodium Phosphate |
| Melengestrol acetate |
Mometasone furoate |
Dexamethasone palmitate |
| Betamethasone acetate |
Beclomethasone dipropionate |
Fluocinolone acetonide |
| Betamethasone Dipropionate |
Betamethasone 17-valerate |
|
Directeur commercial