Raw Steroid Powder Ethinylestradiol / Ethynyl Estradiol CAS 57-63-6 For Treatment Of Female Hypogonadism
Quick Deails
| Nombre del producto |
Ethinylestradiol |
| CAS No. |
57-63-6 |
| Nombre químico |
NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL |
| Peso molecular |
296.41 |
| Fórmula molecular |
C20H24O2 |
| Pureza |
99% |
| Uso |
A synthetic steroid with high oral estrogenic potency |
| Estándar |
USP28 |
| Apariencia |
Polvo cristalino blanco o casi blanco |
| Paquete |
1kg/aluminium foil bag or as your request |
| Pago |
T / T,Western Union,Bitcoin,Pago de Pequeña Cantidad,etc.. |
| Entrega |
After payment 3-7days |
Abstracto
Ethinyl Estradiol is absorbed in the small intestine and reaches a serum peak about 2 hours later. It undergoes extensive metabolism in the liver involving the cytochrome P450 3A4 isoenzyme.
Ethinyl Estradiol and its metabolites are excreted with the bile. Due to the effect of entero hepatic circulation a second peak is seen several hours later. Individually, wide variations exist in the overall absorption process, and can be further modified by drugs that affect the enterohepatic circulation or liver enzymes.
In circulation Ethinyl Estradiol is almost fully bound to plasma albumin. It is metabolized by hydroxylation of the aromatic ring and excreted in both feces and urine, in part as glucuronide and sulfate conjugate.
Ethinyl Estradiol is hormonally effective by activating the estrogen receptor and thus is an estrogen. It finds its most common use in the estrogen-progestin combination preparations of oral contraceptives. Over time, formulations have decreased the Ethinyl Estradiol dose from as high as 100 μg to as low as 10 μg in
Especificación
| Artículo |
Especificación |
Resultados |
| Apariencia |
White to creamy white, inodoro, crystalline powder. |
polvo cristalino blanco |
| Solubilidad |
Insoluble in water; soluble in alcohol, en cloroformo, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides. |
Cumple |
| Identificación |
A:IR B:ultravioleta |
Cumple |
| Rotación óptica específica |
-28°~ -29.5° |
-28.3° |
| Melting range |
180~186ºC |
182.5~185.3ºC |
| Pérdida por secado |
≤1.0% |
0.45% |
| Residual Solvents |
Acetone≤0.5% |
0.08% |
| Ensayo |
97.0~102,0% (on the dried basis) |
99.43% |
| Particle Size |
90% ≤10μ |
Cumple |
| Conclusión |
The product complies with specification in USP34 |
Solicitud
As Estinyl, EE2 was formerly used for hormone replacement therapy in menopause and the treatment of femalehypogonadism, loss of menstruation, dismenorrea, acné, prostate cancer, and breast cancer. Sin embargo, in more recent times, EE2 is mainly used in COCs. In contraception, due to concerns of unopposed estrogen action and the possible increased risk of endometrial cancer that accompanies this, EE2 is formulated in combination with progestins. EE2 is little used in menopausal hormone replacement therapy.
EE2 has been used at very high dosages (1-2 mg / día) in the treatment of prostate cancer.
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| estradiol |
estrona |
Hydrocortisone |
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estriol |
Hydrocortisone acetate |
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|
| Estradiol cypionate |
Diethylstilbestrol |
Prednisone acetate |
| Estradiol enantate |
HEXESTROL |
Bentelan |
| Ethynyl estradiol |
Progesterona |
Betamethasone |
| Algestone acetophenide |
Medroxyprogesterone acetate |
Clobetasol propionate |
| etisterona |
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Halobetasol propionate |
| 19-Norethindrone acetate |
Mifepristone |
Deflazacort |
| Norethisterone Enanthate |
Methyldienedione |
Tazarotene |
| Ethynodiol diacetate |
Eplerenone |
Ecdysone |
| Pregnenolone acetate |
Levonorgestrel |
Desloratadine |
| Lynestrenol |
Allylestrenol |
Prednisolone phosphate sodium |
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Dienogestrel |
Acetato de fluorometolona |
| Cyproterone acetate |
Drospirenone |
Dexamethasone Acetate |
| Megestrol acetate |
pregnenolona |
Fosfato de sodio de dexametasona |
| Melengestrol acetate |
Mometasone furoate |
Dexamethasone palmitate |
| Betamethasone acetate |
Beclomethasone dipropionate |
Fluocinolone acetonide |
| Betamethasone Dipropionate |
Betamethasone 17-valerate |
|
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