Raw Steroid Powder Ethinylestradiol / Ethynyl Estradiol CAS 57-63-6 For Treatment Of Female Hypogonadism
Quick Deails
| Produktname |
Ethinylestradiol |
| CAS-Nr. |
57-63-6 |
| Chemischer Name |
NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL |
| Molekulargewicht |
296.41 |
| Molekularformel |
C20H24O2 |
| Reinheit |
99% |
| Verwendung |
A synthetic steroid with high oral estrogenic potency |
| Standard |
USP28 |
| Aussehen |
Testgegenstände |
| Paket |
1kg/aluminium foil bag or as your request |
| Zahlung |
T/T,Western Union,Bitcoin,Geld Gramm,ect. |
| Lieferung |
After payment 3-7days |
Abstrakt
Ethinyl Estradiol is absorbed in the small intestine and reaches a serum peak about 2 Stunden später. It undergoes extensive metabolism in the liver involving the cytochrome P450 3A4 isoenzyme.
Ethinyl Estradiol and its metabolites are excreted with the bile. Due to the effect of entero hepatic circulation a second peak is seen several hours later. Individually, wide variations exist in the overall absorption process, and can be further modified by drugs that affect the enterohepatic circulation or liver enzymes.
In circulation Ethinyl Estradiol is almost fully bound to plasma albumin. It is metabolized by hydroxylation of the aromatic ring and excreted in both feces and urine, in part as glucuronide and sulfate conjugate.
Ethinyl Estradiol is hormonally effective by activating the estrogen receptor and thus is an estrogen. It finds its most common use in the estrogen-progestin combination preparations of oral contraceptives. Over time, formulations have decreased the Ethinyl Estradiol dose from as high as 100 μg to as low as 10 μg in
Spezifikation
| Artikel |
Spezifikation |
Ergebnisse |
| Aussehen |
White to creamy white, geruchlos, kristallines Pulver. |
Testgegenstände |
| Löslichkeit |
Insoluble in water; soluble in alcohol, in Chloroform, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides. |
Entspricht |
| Identifizierung |
EIN:IR B:UV |
Entspricht |
| Spezifische optische Drehung |
-28°~ -29.5° |
-28.3° |
| Melting range |
180~186ºC |
182.5~185.3ºC |
| Trocknungsverlust |
≤1,0 % |
0.45% |
| Restlösemittel |
Acetone≤0.5% |
0.08% |
| Assay |
97.0~102,0 % (on the dried basis) |
99.43% |
| Partikelgröße |
90% ≤10μ |
Entspricht |
| Fazit |
The product complies with specification in USP34 |
Anwendung
As Estinyl, EE2 was formerly used for hormone replacement therapy in menopause and the treatment of femalehypogonadism, loss of menstruation, dysmenorrhea, Akne, prostate cancer, and breast cancer. jedoch, in more recent times, EE2 is mainly used in COCs. In contraception, due to concerns of unopposed estrogen action and the possible increased risk of endometrial cancer that accompanies this, EE2 is formulated in combination with progestins. EE2 is little used in menopausal hormone replacement therapy.
EE2 has been used at very high dosages (1-2 mg/Tag) in the treatment of prostate cancer.
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|
| Estradiol cypionate |
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Prednisone acetate |
| Östradiol-Enantat |
HEXESTROL |
Bentelan |
| Ethinylestradiol |
Progesterone |
Betamethasone |
| Algestone acetophenide |
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| 19-Norethindrone acetate |
Mifepriston |
Deflazacort |
| Norethisterone Enanthate |
Methyldienedione |
Tazarotene |
| Ethynodiol diacetate |
Eplerenon |
Ecdysone |
| Pregnenolone acetate |
Levonorgestrel |
Desloratadine |
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Allylestrenol |
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Pregnenolon-Rohpulver CAS |
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Mometasone furoate |
Dexamethasone palmitate |
| Betamethasone acetate |
Beclomethasone dipropionate |
Fluocinolone acetonide |
| Betamethasone Dipropionate |
Betamethasone 17-valerate |
|
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