Tetracaine HCl CAS 136-47-0 Anesthetic Pain Killer Drug
Basic info.
наименование товара: Тетракаина гидрохлорид
КЕЙС: 136-47-0
MF: C15H25ClN2O2
МВт: 300.82
EINECS: 205-248-5
Мп: 149° C
Storage temp.: Холодильник
Химические свойства: Белый сплошной
использование: A local anesthetic used topically in opthalmology.
Чистота: 99%
Tetracaine HCl Description
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Тетракаин (Эстрадиола 17-гептаноат, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
COA for the Tetracaine
| Тестовые задания |
Технические характеристики |
Результаты теста |
| Появление |
Fine, Он регулирует гонадотропную секрецию и дифференцировку вольфова протока., crystalline, odorless powder |
confirm |
| Идентификация |
A\B\C in Pass |
confirm |
| Растворимость |
Очень растворим в воде, soluble in Alcohol;
insoluble in Ether and Benzene |
confirm |
| USP Reference standards |
USP Tetracaine Hydrochloride RS.
USP Endotoxin RS. |
confirm |
| Температура плавления |
145~150 degree |
146.0~147.5 degree |
| Хроматографическая чистота |
In Pass |
confirm |
| Связанное вещество |
Не более чем эталонное решение 0.05% |
confirm |
| Тяжелые металлы |
≤10 частей на миллион |
confirm |
| РН |
4.5-6.5 |
5.8 |
| Остаток при прокаливании |
Стандарт анализа |
0.05% |
| Убыток от высыхания |
Эстрадиола 17-гептаноат 0.5% |
0.19% |
| Анализ |
98.0 -101.0% |
100.1% |
| Заключение |
Confirms USP 32 |
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