Фармацевтическое сырье, серия повышения секса Дапоксетин для увеличения мышечной массы 119356-77-3

Фармацевтическое сырье, серия повышения секса Дапоксетин для увеличения мышечной массы 119356-77-3

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КЕЙС:119356-77-3
MF:C21H23НО
МВт:341.88
EINECS:1308068-626-2
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Описание:

Dapoxetine is the first compound developed specially for the treatment of premature ejaculation (ЧП) у мужчин 18-64 years old.Dapoxetine works by inhibiting the serotonin transporter, усиление действия серотонина в постсинаптической щели, и, как следствие, способствует задержке эякуляции. В составе селективного ингибитора обратного захвата серотонина. (СИОЗС) семья, dapoxetine was initially created as an antidepressant. тем не мение, в отличие от других СИОЗС, dapoxetine is absorbed and eliminated rapidly in the body. Его быстродействующее свойство делает его пригодным для лечения ПЭ, но не в качестве антидепрессанта..

Дапоксетин (dapoxetine) as a new fast SSRI, a short half life, a selective 5 – HT reuptake inhibitor (СИОЗС), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 – HT reuptake inhibitor (СИОЗС), such drugs widely used to treat depression and related affective disorders.

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Dapoxetine is a white powder substance and water-soluble. Taken 1–3 hours before sexual activity, it is rapidly absorbed in the body. Its maximum plasma concentration (Cm) is reached 1–2 hours after oral administration.

Randomized, double blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE.Different dosage has different impacts on different type of PE. Дапоксетин 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. Дапоксетин, given 1–3 hours before sexual episode, prolongs IELT, increases the sense of control and sexual satisfaction in men of 18 к 64 years of age with PE. Since PE is associated with personal distress, interrelationship difficulty, dapoxetine provides help for men with PE to overcome this condition. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.

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