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  • Nootropic Sunifiram Powder CAS 314728-85-3 for Memory Enhancement

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    Other Hot-Sale Products (Raw Powder)
    Certification: ISO,USP,GMP
    Model Number: 314728-85-3
    Minimum Order Quantity: 10G
    Delivery Time: 12 hours after payment received,4-7 days to your address
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    • Specifications

    Nootropic Sunifiram Powder CAS 314728-85-3 for Memory Enhancement

    Product details:

    Name Sunifiram
    Systematic (IUPAC) name 1-benzoyl-4-propanoylpiperazine
    CAS number 314728-85-3
    Formula C14H18N2O2
    Appearance white powder
    Application a piperazine derived research chemical which has nootropic effects
    Stock bulk in stock
    Assay 99%

    Sunifiram Description:
    Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).

    This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.

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