Polvo Nootrópico Sunifiram CAS 314728-85-3 para mejorar la memoria
Detalles de producto:
Nombre |
Sunifiram |
Systematic (IUPAC) nombre |
1-benzoyl-4-propanoylpiperazine |
número CAS |
314728-85-3 |
Fórmula |
C14H18N2O2 |
Apariencia |
polvo blanco |
Solicitud |
a piperazine derived research chemical which has nootropic effects |
Stock |
bulk in stock |
Ensayo |
99% |
Descripción de Sunifiram:
Sunifiram (DM-235) es un fármaco ampaquina derivado de la piperazina que actúa como un modulador alostérico positivo de los receptores AMPA, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). Más específicamente, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
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