Raw White Crystal Safe Pharmaceutical Intermediates Phenacetin Pain-Relieving Drug Phenacet Safe Pass
Détail rapide:
Nom du produit: Phénacétine
CAS: 62-44-2
EINECS: 200-533-0
Essai: 99%
Formule: C10H13NO2
MW: 179.2157
Densité: 1.099g / cm3
Water-soluble: 0.076 g / 100 mL
Vapor Pressure: 3.21E-05mmHg at 25 °C
Les usages: Anti-inflammatory drugs
Apparence: White or almost white crystalline powder
Marchés d'exportation: Mondial
Abstrait
Phenacetin is a human carcinogen based on sufficient evidence of carcinogenicity studies in experimental animals. In an 18-month carcinogenicity study, dietary administration of 2.5% phenacetin induced renal cell carcinomas of the renal pelvis and transitional cell carcinomas of the urinary bladder in rats, the tumor incidence in males being greater than in females. In another long-term carcinogenicity study, dietary administration of 0.535% phenacetin for 117 weeks induced renal pelvic tumors in male rats. In B6C3F1 mice of each sex maintained on a diet containing 1.25% ou 0.6% phenacetin for 96 semaines, a dose-related induction of renal tumors was observed in male mice, and urinary bladder proliferative lesions developed in mice of either sex fed 1.25% phenacetin.
Application
Ses effets antalgiques sont dus à ses actions sur les voies sensorielles de la moelle épinière. en outre, phenacetis has a depressant action on the heart, où il agit comme un inotrope négatif. C'est un antipyrétique, agir sur le cerveau pour diminuer la consigne de température. It is also used to treatrheumatoid arthritis (type subaigu) et névralgie intercostale.
Directeur commercial