Pharmaceutical Raw Materials Clobetasol Propionate CAS 25122-46-7 For Inflammatory Treatment Skin Disorders
Supériorité
Zhongshan Latterson Biotechnology Co., Ltd., est une entreprise pharmaceutique complète, qui s'est spécialisé dans la technologie biopharmaceutique 7 années. L'entreprise est située dans la ville de Zhongshan, Province de Guangdong , Chine.
Notre usine couvre une superficie de 33500 mètres carrés, avec un environnement propre et une belle mise en page. Il existe plusieurs ateliers de grande ou moyenne taille et un centre d'assurance qualité et de recherche avec un équipement de pointe. Maintenant, nos principaux produits sont des séries de stéroïdes anabolisants, Série peptidique, Série d'anesthésie locale. Nos produits atteignent le niveau avancé du marché intérieur, dont beaucoup atteignent la norme internationale, les certificats contiennent: KASCHER , ISO 9001:2008 , BPF , SGS.
Abstrait
Clobetasol propionate is part of a group of drugs known as glucocorticoids, which are a type of corticosteroid (ou “steroid” for short). Although glucocorticoids have numerous effects in the body, they are used mostly for their anti-inflammatory or immune-suppressing properties. Clobetasol propionate works for most conditions by decreasing inflammation or suppressing an overactive immune system.Clobetasol propionate is a corticosteroid of synthetic steroid used to treat various skin disorders including inflammation, itching, herpes labialis, eczéma, psoriasis and lichen sclerosus.Clobetasol propionate is also highly effective for contact dermatitis caused by exposure to poison ivy/oak and auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma).
Clobetasol propionate is used as first-line treatment for both acute and chronic GVHD of the skin.
spécification
| Nom du produit |
Clobetasol propionate |
| n ° CAS. |
25122-46-7 |
Emballage extérieur |
1KG/sac |
| Date de production |
2016.05 |
Durée de conservation |
2021.04 |
| Test |
Observation |
Limit |
| La description |
Poudre cristalline blanche |
White to cream crystalline powder |
| Solubilité |
Conforme |
As per USP |
| Identification |
Conforme |
As per USP |
| Melting range |
196C |
About 196ºC |
| Specific optical Rotation(sur base séchée) |
+100.92° |
+98° to +104° |
| Perte au séchage |
0.25% |
Pas plus de 2.0% |
| Résidu à l'allumage |
0.06% |
Pas plus de 0.1% |
| Métaux lourds |
Conforme |
Pas plus de 20 ug/gm |
Chromatographic purity
i)Any individual impurity
Ii)Impureté totale |
0.36%
0.58% |
Not more than1.0%
Not more than2.5% |
| Essai(sur base séchée) |
99.4% |
Not less than97.0%&Not more than102.0% |
Residualsolvents
Methylene chloride
Acetone
Ethyl Acetate
Methanol
DMF |
N.D.
N.D.
N.D.
928.86ppm
N.D.
N.D. |
Pas plus de 600 ppm
Pas plus de 5000 ppm
Pas plus de 5000 ppm
Pas plus de 3000 ppm
Not more than200 ppm
Pas plus de 880 ppm |
Application
Adrenal corticosteroids and adrenocorticotropic hormone drugsClobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,[4] psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
Usage
1. For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe
corticosteroid-responsive dermatoses of the scalp.
2. Topical corticosteroid. Glucocorticoid; anti-inflammatory
How it works
Clobetasol belongs to a class of drugs called topical corticosteroids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Clobetasol works by decreasing your body’s response to inflammation. It also reduces the activity of your immune system. This prevents inflammation and itching and treats your skin condition.
Before using clobetasol cream:
Some medical conditions may interact with clobetasol cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have measles, tuberculosis (TB), chickenpox, shingles, or have had a recent vaccination
if you have a skin infection or thinning of the skin (atrophy)
Some MEDICINES MAY INTERACT with clobetasol cream. Cependant, no specific interactions with clobetasol cream are known at this time.
Ask your health care provider if clobetasol cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
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Directeur commercial