Modèle NON.: CZG-Sarms09
Nom: Aïcar
Autre nom: Acadesine
N ° CAS.: 2627-69-2
Mf: C9h14n4o5
MW: 258.23
Einecs: 220-097-5
Usage: Fat Buring
MOQ: 1 Gram
Espace de rangement: Endroit frais et sec
Apparence: Poudre blanche
Marque déposée: CZG
Forfait transport: Aluminum Foil Bag or as Requirement
spécification: 10g/ bag 50g/ bag 100g/ bag etc
Origine: China Mainland
Code SH: 2937290090
Mechanism of action
The nucleoside form of AICAR, acadesine, is an analog of adenosine that enters cardiac cells to inhibit adenosine kinase and adenosine deaminase. It enhances the rate of nucleotide re-synthesis increasing adenosine generation from adenosine monophosphate only during conditions of myocardial ischemia.In cardiac myocytes, acadesine is phosphorylated to AICAR to activate AMPK without changing the levels of the nucleotides. AICAR is able to enter the de novo synthesis pathway for adenosine synthesis to inhibit adenosine deaminase causing an increase in ATP levels and adenosine levels.