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  • Tetracaine HCl CAS 136-47-0 Anesthetic Pain Killer Drug

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    Other Hot-Sale Products (Raw Powder)
    Certification: iso9001
    Model Number: 136-47-0
    Minimum Order Quantity: 10gram
    Delivery Time: 3-7 working days
    Payment Terms: T/T, Western Union, MoneyGram,bitcoin
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    • Specifications

    Tetracaine HCl CAS 136-47-0 Anesthetic Pain Killer Drug

    Basic info.

    Product Name: Tetracaine HCl

    CAS: 136-47-0
    MF: C15H25ClN2O2
    MW: 300.82
    EINECS: 205-248-5
    Mp: 149°C
    Storage temp.: Refrigerator
    Chemical Properties: White Solid
    Usage: A local anesthetic used topically in opthalmology.
    Purity: 99%

    Tetracaine HCl Description

    Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

    Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

    In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

    COA for the Tetracaine 

    Test Items Specification Test Results
    Appearance Fine, white, crystalline, odorless powder confirm
    Identification A\B\C in Pass confirm
    Solubility Very soluble in water, soluble in Alcohol;
    insoluble in Ether and Benzene
    confirm
    USP Reference standards USP Tetracaine Hydrochloride RS.
    USP Endotoxin RS.
    confirm
    Melting point 145~150 degree 146.0~147.5 degree
    Chromatographic purity In Pass confirm
    Related substance Not more than the reference solution 0.05% confirm
    Heavy metals ≤10ppm confirm
    PH 4.5-6.5 5.8
    Residue on ignition ≤0.10% 0.05%
    Loss on Drying ≤ 0.5% 0.19%
    Assay 98.0 -101.0% 100.1%
    Conclusion Confirms USP 32

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