Vardenafil CAS 224785-91-5 Legal Sex Raw Steroid Hormone Powder
Quick Details :
Product name: VARDENAFIL HYDROCHLORID
Alias: Valdenafil.HCl , VARDENAFIL, HYDROCHLORIDE SALT
CAS No.: 224785-91-5
Assay: 99%
Appearance: White powder
EINECS:
Molecular formula: C23H34Cl2N6O4S
Molecular weight: 306.44
Molecular structure:
Melting point: 214-216°C
Manufacturer: Xinrunde
Usage: It is pharmaceutical raw material,indicated for the treatment of erectile dysfunction
Description
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil’s indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to Sildenafil citrate (Viagra) and Tadalafil (Cialis). The difference between the Vardenafil molecule and Sildenafil citrate is that a nitrogen atom has different position and the change of Sildenafil’s piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both Sildenafil and Vardenafil. Vardenafil’s relatively short effective time is comparable to but somewhat longer than Sildenafil’s.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).Further, Vardenafil lengthens QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as Amiodarone).
Application
Vardenafil’s indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom’s position and the change of sildenafil’s piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil’s relatively short effective time is comparable to but somewhat longer than sildenafil’s.
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation.
COA :
| Item |
Standard |
Result |
| Appearance |
Yellow or light yellow crystalline powder |
Conforms |
| Melting Point |
About 182ºC |
181.5~182.5ºC |
| Solubility |
Conforms |
Conforms |
| Identification |
Positive |
Positive |
| Loss on drying |
≤0.5% |
0.22% |
| Heavy metais |
≤0.002 |
Conforms |
| Residue on ignition |
≤0.1% |
0.06% |
| Related substsnces |
≤0.5% |
0.20% |
| Isotretinoin |
≤0.5% |
0.42% |
| Assay |
97.0~102.0% |
99.70% |
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