Tadalafil /Cialis Powder CAS 171596-29-5 For Male Erectile Dysfunction
Quick Details:
Product Name:Tadalafil
Synonyms:(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
CAS:171596-29-5
MF: C22H19N3O4
MW:389.4
EINECS: 200-835-2
Chemical Properties:White to off-white cyrstalline solid
Assay:99%
MP: 298-300°C
Uses:It is a kind of PDE-5 inhibitors which can be used for the treatment of male erectile dysfunction. It is also the second generation of phosphodiesterase type 5 inhibitors used to treat male erectile dysfunction.
Tadalafil COA:
| Items |
Enterprise |
Result |
| Description |
Off-white or white crystalline powder |
White crystalline powder |
| Identification |
IRHPLC |
Conform to standard |
| Loss on drying |
≤0.5% |
0.1% |
| Residue on ignition |
≤0.1% |
0.03% |
| Heavy metals |
≤0.002% |
<0.002% |
| Related substances |
Individual impurity≤0.1% |
0.03% |
| Total impurities≤0.3% |
≤0.3% |
| Assay |
97.5~102.5% |
99.82% |
Applications:
Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil’s pharmacologic distinction is its longer half-life (17.50 hours) – compared to sildenafil (4.0–5.0 hours) and vardenafil (4.0–5.0 hours) – resulting in longer duration of action, and so partly responsible for “The Weekend Pill” sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil’s daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.
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