Sunifiram CAS 314728-85-3 Pharmaceutical Raw Materials Ampakine Nootropic 

Quick Details

What Is Sunifiram?

Sunifiram, also known as 1-benzoyl-4-propanoylpiperazine is a nootropic that was only first researched in the year 2000.

It has a similar chemical structure to Piracetam but initial studies show that it is significantly more potent than this widely used racetam.

Sunifiram so far shows very positive results as memory enhancer and it is currently being investigated for potential treatment of Alzheimer’s and other diseases related to cognitive decline.

User reviews and Sunifiram logs point to the fact that this supplement makes information recall much easier and helps you think more clearly. Sunifiram is being compared to Noopept quite a bit because of their similar potency levels.

Initial observations suggest that Sunifiram is better as a memory booster while Noopept might have an edge on increasing focus and alertness.

Description

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2. Sunifiram is highly effective at boosting memory function as well as attention span, learning, decision making and alertness.A lot of initial reviews and user experiences suggest that Sunifiram could become one of the most popular nootropic study aids for improving concentration.

3. Sunifiram has a similar chemical structure to Piracetam but initial studies show that it is significantly more potent than this widely used racetam.Sunifiram so far shows very positive results as memory enhancer and it is currently being investigated for potential treatment of Alzheimer’s and other diseases related to cognitive decline.

4. User reviews and Sunifiram logs point to the fact that this supplement makes information recall much easier and helps you think more clearly. Sunifiram is being compared to Noopept quite a bit because of their similar potency levels.Initial observations suggest that Sunifiram is better as a memory booster while Noopept might have an edge on increasing focus and alertness.

Application

The exact mechanism to explain how Sunifiram is able to have such a strong cognitive benefit is yet to be found, but scientist have identified some interesting models to show how some of these attributes may be better understood. One such mechanism is that of NMDA signaling which was confirmed after Sunifiram dosages were maintained for over 7 days.

This can explain some of the NMDA-dependent Long Term Potentiation seen with Sunifiram use.Further studies have shown rodents with memory impairment (centered around the hippocampus) benefitted from Sunifiram administration, when their ability to complete training sessions was measured. Finally, Sunifiram injections were able to cause the release of acetylcholine, which was detected in the prefrontal cortex of laboratory mice.

Sunifiram(DM-235) COA

Dosage and How to Take?

Sunifiram is incredibly concentrated compared even to the strongest racetams like Pramiracetam. You will see positive effects from a dosage as small as 4 mg though many people typically take between 5-8 mg at a time. A Sunifiram dose of 10 mg is more likely to cause a stimulant effect similar to Adderall.
Taking a 10 mg Sunifiram dosing is not toxic and not likely to cause serious negative side effects, however you may experience increased body temperature and perspiration. You should start with a half dose of 3 mg for your first week or so of taking this ampakine nootropic and then only increase the dosage if you feel comfortable.

Sunifiram Effects and Benefits

Sunifiram works very similarly to other racetams by stimulating many of the same receptors just in different ways. The primary effect of taking Sunifiram is stimulation of AMPA receptors (hence which this drug is considered an AMPAkine). In clinical trials, patients given the AMPA antagonist NBQX and then given Sunifiram saw increased AMPA receptor activity. AMPA receptors are responsible for how much glutamate is produced in the brain. Glutamate is perhaps the most important neurotransmitter in the brain, responsible for communicating excitatory transmissions, forming connections between synapses, and for regulating brain cell survival.

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