Sodium picosulfate Pharmaceutical Raw Materials 10040-45-6 For Laxative

Basic Info.

Description:

Sodium picosulfate (INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Sodipic Picofast, Laxoberal, Laxoberon, Purg-Odan, Picolax, Guttalax, Namilax, Pico-Salax and Prepopik among others. PicoPrep is based on Sodium picosulphate.

Usage:

Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.

Medical Effect:

1.Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12-24 hours to work, since it works in the colon.

2.The most common side effects of picosulfate are abdominal cramps and diarrhea.

3.The use of sodium picosulfate has also been associated with certainelectrolyte disturbances, such as hyponatremia and hypokalemia.[6]Patients are often required to drink large amounts of clear fluids as well as rehydrate to reestablish the electrolyte balance.

Mechanism of action:

Sodium picosulfate is a prodrug. It has no significant direct physiological effect on the intestine, however it is metabolised by gut bacteria into the active compound 4,4′-dihydroxydiphenyl-(2-pyridiyl)-methane (DPM, BPHM). This compound is a stimulant laxative and increases peristalsis in the gut.

Sodium picosulfate is typically prescribed in a combined formulation withmagnesium citrate, an osmotic laxative. This combination is a highly effective laxative, often prescribed to patients for bowel cleansing prior to colonoscopies.

FAQ:

Q how can I be sure the powder contains right substances?
S We can offer you the cretificate of analysis of products and HPLC,Besides, After Receiving the goods, you can send it to detect, or buy a test kit steroid, detect it yourself.
Q What’s the guarantees that you will send items after payment
S The feedback of customers:
Tracking Number :DHL3292172505
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We are regular company, we guarantee that after the receipt of your payment we will arrange the shipment within 24 hours , and provide the tracking number, you can keep track of it.so,don’t hesitate to let me serve you.
Q What kind of payments does you support?
S T/T, Western Union, Money Gram and Bitcion are accepted.
Q What’s the MOQ?
S Generally speaking, the MOQ is 10 gram, but we also can provide you samples for quality inspection.
Q Do you charge for the samples?
S According to our company policy, we just charge the samples based on EXW price. And we will return the samples fee during the next order.
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S Sure,we will adopt safe and discreet package.If you have a request for packing, please tell us,Any good ideas are welcomed.
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