Pharmaceutical Chemical Nootropic Raw Materials Powder Phenibut CAS 1078-21-3 For Nutrition Supplement

Гексадрон – мощный анаболик.

1.Phenibut is a derivative of the naturally occurring inhibitory neurotransmitter GABA.

2.Phenibut is used by bodybuilders to reduce fatigue and improve neurological functions.

3.Phenibut has been and is still used medically to treat stress, relieve tension, improve sleep, and as a potentiate for other medications.

Преимущества

phenibut is a gaba receptor agonist and also causes the release of gaba. similar to baclofen, phenibut is an agonist at gaba(б) receptors, although it does have some effect on gaba(а) receptors as well. it is possible that phenibut has a higher activity at central gaba(б) receptors than peripheral ones. the role of the gaba(б) receptor is not well-established, although research in the last seven years has significantly increased our understanding of this receptor. the most well-established role of gaba(б) receptors is inhibition of the release of some neurotransmitters, and it may also serve as a negative feedback mechanism for gaba release

because of the structural similarity to pea, phenibut may share some similarities and differences with it. when phenibut is administered along with pea, it antagonizes many of its effects, such as promotion of anxiety, promotion of seizures, and hyperthermia. this has lead some to postulate that antagonism of pea, rather than the gaba-mimetic activity, may be the important mechanism of action for tha anxiolytic effect of phenibut. phenibut also increases dopamine levels, and it has been postulated that the structural similarity to pea may play a role in this effect.

Avail

Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Следовательно, you tend to have localised or ‘focal’ symptoms. Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a number of different conditions, including diabetes (where it is called diabetic neuropathy) and shingles(where it is called postherpetic neuralgia).

Медицинское использование

Pregabalin is useful when added to other treatments, when those other treatments are not controling partial epilepsy. Its use alone is less effective than some other seizure medications. It is unclear how it compares to gabapentin for this use.

Neuropathic pain

The European Federation of Neurological Societies recommends pregabalin as a first line agent for the treatment of pain associated with diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. A minority obtain substantial benefit, and a larger number obtain moderate benefit. Other first line agents, including gabapentinand tricyclic antidepressants, are given equal weight as first line agents, and unlike pregabalin, are available as less expensive generics.

Pregabalin is not recommended for certain other types of neuropathic pain such as pain that of trigeminal neuralgia or HIV infection and its use in cancer-associated neuropathic pain is controversial.There is no evidence for its use in the prevention of migraines and gabapentin has been found not to be useful. It has been examined for the prevention of post-surgical chronic pain, but its utility for this purpose is controversial.

Anxiety disorders

Therapeutic effects of pregabalin appear after 1 week of use and is similar in effectiveness to venlafaxine, but pregabalin has demonstrated superiority by producing more consistent therapeutic effects for psychic and somatic anxiety symptoms.Long-term trials have shown continued effectiveness without the development of tolerance, а также, кроме того, , it has a beneficial effect on sleep and sleep architecture, characterized by the enhancement of slow-wave sleep. and produces less severe cognitive and psychomotor impairment.

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