Health Care White Crystalline Effictive Tetracaine Pharmaceutical Raw Materials

Health Care White Crystalline Effictive Tetracaine Pharmaceutical Raw Materials

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Описание

Tetracaine was patented in 1930 and came into medical use in 1941.
Входит в список основных лекарственных средств Всемирной организации здравоохранения., the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 1.34 к 1.63 USD per 10 ml bottle.

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1. In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
2. Tetracaine is the T in Tac, a mixture of 5 к 12 per cent tetracaine, 5М(per myriad), a half per mille (0.5‰), Кулинарные рецепты .05 per cent (1 part in 2000) , а также 4 Кулинарные рецепты 10 per cent hydrochloride used in ear, нос & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ухо, or other sensitive locations.
3. Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.