Procaine HCL Procaine Hydrochloride Local Anesthetic Powder for Pain Killer

Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.

Procaine Hydrochloride​ Quick Details :

Procaine Hydrochloride Chemical name:4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride

Synonyms :Amide, Procaine Hydrochloride, Procainamide Hydrochloride ; Novocainamide Apo-Procainamide Hydrochloride ;Rhythmin ; Procanbid Hydrochloride ; Novocainamide Hydrochloride ; Novocamid Hydrochloride ; Procainamide HCl Procanbid
Molecular weight:271.79
Molecular formula:C13H21N3O.HCl
CAS Number:614-39-1
Assay: 99%
EINECS: 200-077-2
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Appearance: White crystalline powder
Storage instructions Store at +4°C.
Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overview :Soluble in water to 100 mM and in ethanol to 100 mM
Usage: Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.

Procaine Hydrochloride Description:

Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.

Procaine HCL is actually a very simple combination of two B vitamins, PAPA (P-aminobenzoic acid) and DEAE (diethylaminoethanol) buffered and stabilized with benzoic acid and potassium metabisulfite for more effectiveness inside the body. Procaine hydrochloride is a compound combination of PABA and DEAE, a vitaminic substance first synthesized in 1905 by a German chemist, Dr. Albert Einhorn, who was looking for a simple, non-addictive anesthetic.

Procine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine HCl (procaine hydrochloride) is the active ingredient in Gerovital H3(GH3) and in the Vitacels 3 through 8. Procaine HCl is broken down rapidly by enzymes in the blood stream into PABA and DEAE. The PABA and DEAE are rapidly conjugated and removed from the blood and excreted from the body. Because of this procaine HCl and its breakdown products (metabolites) are unable to get into the cells in any great quantity to produce benefits. Procaine HC will produce some benefits by itself, but they are very limited.

Procaine Hydrochloride Applications :

Procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.

Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine Hydrochloride​ Specification:​

COA:

HPLC:

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