Pharmaceutical Raw Materials Sex Enhancement SeriesTadalafil for Muscle Gain 171596-29-5

Pharmaceutical Raw Materials Sex Enhancement SeriesTadalafil for Muscle Gain 171596-29-5

Abstract

CAS:171596-29-5
MF:C22H19N3O4
MW:389.4
EINECS:200-835-2
Melting point:298-300°C
alpha D20 +71.0°
Flash point:2℃
storage temp. Hygroscopic, -20?C Freezer, Under Inert Atmosphere
solubility DMSO: soluble20mg/mL, clear
color white to beige
InChIKeyWOXKDUGGOYFFRN-IIBYNOLFSA-N

Description:

Tadalafil (Cialis) is also a PDE5 inhibitor that increases the level of cyclic guanosine monophosphate (cGMP) in cavernous smooth muscle cells. Whereas cGMP is a second messenger for the vasodilator effects of nitric oxide causing smooth muscle relaxation, which in turn leads to penile erection; however the mechanism by which cGMP stimulates relaxation of the smooth muscles remains to be elucidated.

Applicant

Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil (Adcirca) is used to improve the ability to exercise in people with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works to treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily.

COA