Pharmaceutical Raw Materials Paracetamol 103-90-2 For Relieving Pain

Pharmaceutical Raw Materials Paracetamol 103-90-2 For Relieving Pain

Abstract

CAS:103-90-2
MF:C8H9NO2
MW:151.16
EINECS:203-157-5
Melting point:168-172 °C(lit.)
Boiling point:273.17°C (rough estimate)
Density 1,293 g/cm3
refractive index 1.5810 (rough estimate)
Flash point:11 °C
storage temp. Store at RT
solubility ethanol: soluble0.5M, clear, colorless
form Crystals or Crystalline Powder
color White
PH5.5-6.5 (H2O, 20℃)(saturated solution)
explosive limit15%(V)
Water Solubility 14 g/L (20 ºC)
Merck 14,47
BRN 2208089
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N

Description

Paracetamol, also known as paracetamol, is chemically known as n-acetyl-p-aminophenol, a widely used over-the-counter painkiller (analgesic) and an antipyretic (antipyretic). In the United States (USAN) and Japan, acetaminophen is the name of this drug; paracetamol is approved in various international settings (INN, AAN, BAN, etc.). Common names in the English market are Tylenol and Panadol.

Paracetamol is used by people of all ages to reduce fever. The World Health Organization (WHO) recommends that paracetamol in children only have a fever temperature greater than 38.5 ° C (101.3 ° F). The efficacy of paracetamol itself in children with fever has been questioned, and a meta-analysis has shown that it is not as effective as ibuprofen. Paracetamol is used to relieve pain. The American College of Rheumatology recommends paracetamol as one of several treatment options for hip, hand or knee arthritis pain that has not improved with exercise and weight loss. The 2015 review; however, the study found that it has only minor benefits for osteoarthritis.

Applicant

Paracetamol is a mild painkiller. It is commonly used to relieve headaches and other minor pains and is a major component of many cold and flu therapies. In combination with opioid analgesics, paracetamol can also be used to treat more severe pain, such as postoperative pain and palliative care in patients with advanced cancer. Although paracetamol is used to treat inflammatory pain, it is usually not classified as a non-steroidal anti-inflammatory drug because it exhibits only weak anti-inflammatory activity.

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