Pharmaceutical Raw Materials ingredients Ketoprofen Analgesic Powder
Quick Detail:
English name: ketoprofen
Alias: 2- (3-benzoylphenyl) propionic acid; (S) – (+) – ketoprofen; S – (+) – Ketoprofen; S) -ketoprofen; Dexketoprofen; (2S) -2- (3-benzoylphenyl) propanoic acid ; (S) – (+) – Ketoprofen
CAS: 22071-15-4
EINECS Number: 244-759-8
Formula: C16H14O3
MW: 254.2806
Molecular Structure:
Description
ketoprofen,drinking and other non-steroidal anti-inflammatory drugs used in conjunction, will increase the gastrointestinal side effects, but also cause the risk of ulcers.
ketoprofen, aspirin or other salicylic acid drugs with the same time, can not increase the efficacy of gastrointestinal side effects and increased incidence of bleeding tendency.
ketoprofen, anticoagulant with the use of increased risk of bleeding.
ketoprofen should not be used with methotrexate to prevent poisoning.
ketoprofen, probenecid and verapamil, nifedipine with the use, pay attention to reduce the dose; with digoxin with the time, pay attention to adjust the digoxin dose.
Uses for aryl alkyl acid compounds. With analgesic, anti-inflammatory and antipyretic effect. Anti-inflammatory effect than ibuprofen strong side effects, low toxicity. Oral easily absorbed from the gastrointestinal tract. After 1 dose, about o. 5 to 2 hours up to plasma peak concentration. And t 1/2 is 1.6 to 1.9 hours. In the blood and plasma protein binding strong. In the 24 hours from the urinary excretion rate of 30% to 90%. Mainly in the form of glucuronic acid excretion. For rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, joint hard spondylitis and gout, etc.
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