What’s Pramiracetam?
Ever since the discovery of the racetams in the 1970’s, the racetam family of compounds has been a compelling route for people trying to improve general cognition, memory, and learning capabilities.
In the world of nootropics, the racetams are the go-to nootropics for boosting brain power. While there is some variety of racetam forms, and not all racetams are as well understood as the parent compound, one of the more widely known and studied is Pramiracetam.
Pramiracetam (N-[2-(dipropan-2-ylamino)ethyl]-2- (2-oxopyrrolidin-1-yl)acetamide) is a GABA-like compound derived from the original racetam. The chemical difference between the two is that Pramiracetam has a dipropan-2-ylaminoethyl group rather than an amide.
Pramiracetam is remarkable for high oral-bioavailability and high potency. For this reason, users take Pramiracetam in smaller doses than it’s prototype.
This more potent racetam is sometimes taken as an alternative to weaker racetams for people who don’t feel they give them the sense of well-being that they are after or people who don’t want to take as much powder as less potent racetams can require.
Specification:
| ITEM |
SPECIFICATION |
RESULT |
METHOD |
| Appearance |
White powder, neutral odor, highly hygroscopic |
Conforms |
Visual |
| Identification |
Standard solution and test solution same spot,RF |
Conforms |
TLC |
| Specific Optical |
-2.4°~ -2.8° |
-2.72° |
|
| Heavy metals (as PB) |
≤10ppm |
Conforms |
AAS |
| Sulfate (SO4) |
≤0.02% |
Conforms |
Colorimetry |
| Chloride (Cl) |
≤0.02% |
Conforms |
Colorimetry |
| Phosphate Ion (P) |
≤5ppm |
Conforms |
Colorimetry |
| Residual solvent(ethanol) |
≤1.0% |
Conforms |
HS-GC |
| pH |
4.5~7.0 |
5.10 |
|
| Related substance |
Spot not bigger than standard solution spot |
No spot |
TLC |
| Water Content |
≤2% |
0.26% |
KF |
| Assay (dried basis) |
98.0%–102.0% |
99.48% |
Potentiometric titration |
| Assay (dried basis) |
98.5%–100% |
99.2% |
HPLC |
How Pramiracetam Works?
It’s believed that Pramiracetam is absorbed within the intestine, finding its way into the bloodstream.
After approximately half hour, it generally reaches its maximum potential. Once it is transported to the brain, it has an effect on Acetylcholine receptor sites. Acetylcholine is a neurotransmitter that has a direct effect on cognitive functions. It is thought that the acetylcholine sites improve in efficiency.
Pramiracetam binds to receptor sites, increasing the efficiency of Acetylcholine in the brain. There is also a significant increase in blood flow within to the brain. When oxygen uptake is increased, there is also an increase in glucose metabolism. This is what may allow users to feel alert and have a sense of clarity.
It is also believed that Pramiracetam may enhance the uptake of choline to the hippocampus. This area of the brain is responsible for memory and spatial navigation.Therefore, learning and memory tend to improve.
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