New Weight Loss Powder Cetilistat,99% Pharmaceutical Raw Materials Cetilistat

Cetilistat
CAS NO.:282526-98-1
MF:C25H39NO3
MW:401.58
Appearance:white powder
Purity:99%

Cetilistat is a long-acting and potent specific gastrointestinal lipase inhibitor that inactivates the enzyme by forming covalent bonds with the active serine sites in the gastric and small intestine gastric lipase and pancreatic lipase And play a therapeutic role, inactivated enzyme can not be the food fat is mainly triglycerides hydrolysis can be absorbed free fatty acids and monoacyl glycerol. Undigested triglycerides can not be absorbed by the body, thereby reducing calorie intake and controlling body weight. The biggest advantage of the drug is not applied to the nervous system, does not affect the gastrointestinal tract of other enzyme activity, not absorbed that is not into the blood, do not suppress appetite, without limiting the diet. After 24 hours of treatment can be defecation phenomenon (water floating a lot of oil droplets), that is, to exclude the digestion of fat. He was similar to Roche’s Xenical Orlistat, but compared with the latter, some of its adverse reactions such as excretory incontinence and flatulence were much less. It can be safer and more tolerant.

A randomized placebo-controlled study of 12-week randomized placebo control for obese patients who received a new lipase inhibitor in the new regimen (ATL-962) was confirmed to be 12 weeks of medication, 60 mg each time, 3 times a day 3.3kg; each 120mg, 3 times a day, weight loss 3.5kg; each 240mg, 3 times a day, weight loss 4.1kg. Hyperlipidemia in patients with blood cholesterol levels and low-density lipoprotein cholesterol levels decreased by 3 ~ 11%. Use the new profit he lost weight, 12 weeks effective.

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