MF:C14H23ClN2O
MW:270.8
EINECS:200-803-8
Synonyms:2-DIETHYLAMINO-N-(2’6′-DIMETHYLPHENYL)ACETAMIDE HCL;2-DIETHYLAMINO-N-[2,6-DIMETHYLPHENYL]ACETAMIDE HCL;ALPHA-(DIETHYLAMINO)-2′,6′-ACETOXYLIDIDE HYDROCHLORIDE;A-(DIETHYLAMINO)-2 6-DIMETHYLACETANILIDE HYDROCHLORIDE;LIGNOCAINE HYDROCHLORIDE;LIDOCAINE HYDROCHLORIDE;LIDOCAINE HCL;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamidmonohydrochloride
| Product Name |
Lidocaine Hydrochloride |
| Other Name |
2-(Diethylamino)-N-(2,6-dimethylphenyl) acetamide hydrochloride |
| Assay (%) |
≥99.5 |
Odor |
Characteristic |
| Color |
White crystalline powder |
Cas No. |
73-78-9 |
| Molecular Formula |
C14H23ClN2O |
Molecular Weight |
270.7982 |
| Standard |
BP2007/USP31 |
| Function |
Main functions are as follows:
1.Local anesthetic.
2. Treating Epilepsy.
3. Treating Asthma. |
| Applications |
Main applications are as follows:
Applied in pharmaceuticalfields. |
| Packing |
1kgor 5kg/bag, 25kg/drum |
| Shelf Life |
24 months |
| Storage |
Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation. |
| ITEMS |
SPECIFICATIONS |
RESULTS |
| Appearance |
White crystalline powder |
Pass |
| Purity |
99.00%-101.00% |
99.52% |
| Identification |
Chloridate |
Positive |
| Test A |
Positive |
| Melting point |
74-79 degree |
76-78 degree |
| Appearance of solution |
Clear and colourless |
Pass |
| Water |
5.5-7.0% |
6.7% |
| Acidity PH |
4.0-5.5 |
5.2 |
| Sulphated ash |
0.10% max |
0.08% |
| Heavy metals |
5ppm max |
Pass |
| 2, 6-Dimethylaniline |
100ppm max |
Pass |
|
Application
Lidocaine hydrochloride with a strong penetrating, diffuse strong, fast onset characteristics, anesthetic potency twice and procaine, and toxicity 1.5 minutes after anesthetic drugs, anesthesia for 1 to 1.5 hours. Can inhibit the absorption of central nervous system, and can suppress ventricular automaticity, shortened refractory period, the control room can be used as tachycardia, treating premature ventricular contractions, ventricular tachycardia and ventricular fibrillation and other arrhythmias symptoms. Disease of the heart itself or arrhythmias caused by cardiac glycosides are valid, the bad effects of supraventricular tachycardia. This product is the role of fast, short duration, oral invalid, often as an intravenous injection. As local anesthetics, lidocaine same mechanism of action, the role of strength, speed is also very similar to the onset, longer duration, low toxicity, accumulation of small. Invasive surgery for a variety of clinical anesthesia, epidural, conduction anesthesia. A maximum amount of 60mg, infiltration anesthesia with 0.5% to 1% solution; 2%, 3% solution for nerve block and epidural anesthesia.
Active Pharmaceutical Ingredient (API), Local anesthetic. Mainly used for clinical anesthesia, epidural anesthesia, anesthesia (including thoracoscopy or abdominal surgery for mucosal anesthesia) and nerve conduction block. Also be used for acute myocardial infarction and ventricular tachycardia premature ventricular contractions, can be used to digitalis toxicity, cardiac surgery and cardiac catheterization-induced ventricular arrhythmias. But arrhythmias are usually ineffective.
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