High Quality Pharmaceutical Raw Materials Levosulpiride CAS 23672-07-3
Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.
Product Name: Levosulpiride
Product Details:
Product Name : Levosulpiride
Synonyms: (S)-(-)-SULPIRIDE;(S)-(-)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE;(S)-5-AMINOSULFONYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXYBENZAMIDE;(-)-N-1-[ETHYLPYRROLIDIN-2-YLMETHYL]-2-METHOXY-5-SULFAMOYLBENZAMIDE;(s)-(-)-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide;(s)-(-)-o-anisamid;5-(aminosulfonyl)-n-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-benzamid(;levopraid
CAS: 23672-07-3
MF: C15H23N3O4S
MW: 341.43
Product Categories: API;Dopamine receptor;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Chiral Reagents;Other APIs
Melting point : 183-186 °C(lit.)
Storage temp. : 2-8°C
Merck : 13,9080
Chemical Properties : White Solid
Usage : dopamine receptor antagonists
Usage : Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic .
Description:
Levosulpiride is a substituted benzamide antipsychotic, reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels. It is an atypical neuroleptic and a prokinetic agent. Levosulpiride is also claimed to have mood elevating properties. Levosulpiride is used in the treatment of psychoses, particularly negative symptoms ofschizophrenia, anxiety disorders, dysthymia, vertigo, dyspepsia, irritable bowel syndrome and premature ejaculation.
Levosulpiride is a substituted benzamide antipsychotic , reported to be a selective antagonist of dopamine D2 receptor activity on both central and peripheral levels . It is an atypical neuroleptic and a prokinetic agent. Levosulpiride is also claimed to have mood elevating properties .
Chemically, it is the (S)-(−)-enantiomer of sulpiride .
Application:
1. Antipsychotic drugs to treat neurological schizophrenia. is also used for intractable vomiting, peptic ulcer, and traumatic brain injury, dizziness, headache
2. Also used for intractable vomiting and peptic ulcer.
3. Antiemetic
4. Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.
5. Similar effect as sulpiride, but the dos
Function:
psychoses
particularly negative symptoms of schizophrenia
anxiety disorders
dysthymia
vertigo
dyspepsia
irritable bowel syndrome
premature ejaculation.
Levosulpiride is not currently licensed for treatment of premature ejaculation in the UK or other European countries.
COA:
Results of Analysis Tests |
Test Items |
Specification |
Results of Analysis |
Appearance |
White or almost white crystalline powder |
Positive |
Identificantion |
Litmus paper turns blue from red |
Conforms |
Melting Point |
184ºC~189ºC |
185.0ºC~188.8ºC |
Assay |
98.0~102.0% |
0.9995 |
PH |
8.0~10.0 |
9.25 |
Specific rotation |
-65~-70° |
-65.30° |
Loss on drying |
≤0.5% |
0.0002 |
Chloride |
≤100ppm |
Pass |
Heavy metals |
≤10ppm |
Pass |
Iron content |
≤10ppm |
Pass |
Related substances(TLC) |
≤10ppm |
Pass |
Residue on ignition |
≤0.1% |
0.0002 |
Conclusion |
The specification comply with Enterprise standard |
age of Levosulpiride is only half or less, thus the side effects is less.
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