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  • High 99% Purity CAS 2627-69-2 No Side Effect Aicar

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    Other Hot-Sale Products (Raw Powder)
    Certification: GMP
    Model Number: 2627-69-2
    Minimum Order Quantity: 5g
    Delivery Time: 5-7 days after received your payments
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    • Specifications

    High 99% Purity CAS 2627-69-2 No Side Effect

    Product details:

    Product description
    Quick Detail:
    Acadesine
    Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
    CAS: 2627-69-2
    EINECS: 220-097-5
    Molecular Formula: C9H14N4O5
    Molecular Weight: 258.23
    Assay: 98%
    Apperance: White or off-white powder.
    Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

    Description:

    Aicar is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.

    Aicar is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).

    Aicar can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

    AICAR COA:

    CAS No: 2627-69-2 Formula: C9H14N4O5
    Manufacturing Date:Mar.15th,2015 Batch No: TCS20150315
    Expiry Date: Mar.14 th,2017 Quantity: 2.5kg

    TESTS SPECIFICATIONS RESULTS
    Description White powder, or Off-White Solid powder Off-White Powder
    Identification H-NMR Conform
    LCMS Conform
    Melting point 215 – 216 ℃ Complies
    Loss on drying ≤0.5 % 0.18%
    Heavy metals ≤10ppm Conform
    Total impurities ≤3.0 % 0.75%
    Assay (HPLC) > 98.0 % 99.10%
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