Pharmaceutical Raw Materials Trilostane For Breast Cancer Treatment
Supériorité
Zhongshan Latterson Biotechnology Co., Ltd., est une entreprise pharmaceutique complète, qui s'est spécialisé dans la technologie biopharmaceutique 7 années. L'entreprise est située dans la ville de Zhongshan, Province de Guangdong , Chine.
Notre usine couvre une superficie de 33500 mètres carrés, avec un environnement propre et une belle mise en page. Il existe plusieurs ateliers de grande ou moyenne taille et un centre d'assurance qualité et de recherche avec un équipement de pointe. Maintenant, nos principaux produits sont des séries de stéroïdes anabolisants, Série peptidique, Série d'anesthésie locale. Nos produits atteignent le niveau avancé du marché intérieur, dont beaucoup atteignent la norme internationale, les certificats contiennent: KASCHER , ISO 9001:2008 , BPF , SGS.
Détail rapide:
Trilostane
N ° CAS.: 13647-35-3
Pureté: 98.5%min
MF: C20H27NO3
EINECS No.: 237-133-0
Apparence: White to off-white power
Type: Antineoplastic Agents
Grade Standard: Qualité médicale
Emballage: As customers requirments
Usage: Anti-tumor drugs and immunosuppressants
La description
Trilostane, that is 4α, 5α-epoxy-2-cyano-3,17β-diol, can reversibly inhibit 3β-hydroxy steroid dehydrogenase and △5, 4-isomerase in the adrenal cortex to block the biosynthesis of mineralocorticoid and glucocorticoid. Dans 1980, it was approved for the treatment of hyperaldosteronism and cortisol excess disease in the United Kingdom. Dans 1985, it was approved for the treatment of Cushing’s syndrome in the United States, which is adrenal cortex hyperactivity disorder. In view of the older animals, especially older dogs are susceptible to Cushing’s syndrome. Trilostane can relieve the disease symptoms of more than 90% of dogs, and improve their quality of life. So the drug has also been granted for the treatment of animals in the United Kingdom. Trilostane itself has no hormonal activity. Its side effects is less, and its safety and tolerability are also particularly good.
Application
1) Trilostane,The anti estrogen steroids drug Trilostane was previously available in the United Kingdom for use in humans under the brand name Modrenal for the treatment of Cushing’s disease and for breast cancer. It was approved in the United States in 2008 for the treatment of Cushing’s disease (hyperadrenocorticism) in dogs under the brand name Vetoryl.
2) It was available by prescription in the UK under the Vetoryl brand name for some time before it was approved in the US. The drug is also used to treat the skin disorder Alopecia X in dogs. It is also the first drug approved to treat both pituitary- and adrenal-dependent Cushing’s in dogs. This prescription drug works by stopping the production of cortisol in the adrenal glands.
3) Trilostane,The anti estrogen steroids drug Vetoryl is used to treat Cushing’s syndrome (also known as Cushings disease or hyperadrenocorticism). This is a hormone problem associated with abnormally high levels of cortisone in the blood stream of affected dogs. The main symptoms caused are excessive thirst and hunger. It also affects the dog’s appearance and reduces its quality of life. Dogs may show hair loss, weight gain, lethargy, loss of bladder control and a bloated stomach.
4) Trilostane,Cushing’s disease is a condition that will be present in the dog’s system for the rest of its life and will need to be treated continually. Vetoryl tackles this problem in the pituitary and adrenal glands. Cortisol levels are reduced which leads to a reduction in symptoms and Vetoryl can make a difference in just three months.
5) Trilostane,The capsules are available in four strengths depending on the size of the dog and should only be prescribed by a vet. There are a number of contra-indications which should be taken into consideration prior to treatment. Dogs that are pregnant or who have problems with the liver or kidneys should not take this medication.
Les indications
Trilostane can inhibit 3β-dehydrogenase in the synthesis of corticosteroids, and decrease the synthesis of cortisol and aldosterone. It also can be used in the treatment of Cushing’s syndrome (hypercortisolism) and primary aldosteronism. But the efficacy to treat Cushing’s syndrome (hypercortisolism) is not as metyrapone. This product also has a significant role in lowering blood testosterone levels, which may be related with that its synthesis is inhibited.
FAQ
1.comment emballer?
Nous avons une équipe professionnelle pour l'emballage et l'expédition. Manière spéciale d'expédier 100 grammes à 100 kg de poudres à la fois dans votre pays. Une expédition rapide et discrète pourrait être organisée pour le passage des douanes Garanti.
2.comment livrer?
Divers moyens sont pris en charge tels que DHL, TNT, FEDEX, HKEMS, UPS, etc.
3.Combien de temps le produit pourrait être expédié?
La plupart des poudres sont en stock, des échantillons gratuits sont disponibles, le produit peut être expédié dans les 24 heures après réception du paiement.
4.y a-t-il des certifications?
Bien sûr, nous avons déjà obtenu la certification ISO9001, vous pouvez nous faire confiance,nous sommes un fabricant fiable.
5.qu'en est-il du taux de passage des douanes?
Il est inutile de s'inquiéter du passage des douanes.notre société 100% passer au Royaume-Uni, Norvège, Pologne, Espagne, Etats-Unis, Canada, Brésil; 98% pass to Germany, Russie, Australie, Nouvelle-Zélande.
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