Sildenafil Citrate CAS 171599-83-0 Sex Enhancement Drugs Anti Estrogen

Sildenafil Citrate CAS 171599-83-0 Sex Enhancement Drugs Anti Estrogen

Product Details:

Nom du produit:Sildenafil

Synonyme:Viagra
CAS: 139755-83-2
EINECS:200-659-6
Essai: 99% min.
Formule moléculaire: C22H30N6O4S
Masse moléculaire: 474.58
Emballage: 1kg net/foil bag, 5kg/fût.
Point de fusion:187-189°C
Storage condition:Réfrigérateur
Livraison: courrier expresse.
Personnage: White or almost white crystalline powder, inodore, bitter astringent taste, insoluble in water and ethanol.

Description du produit:

Dans 16 separate 4-24 week trials of men (sur 18 years old) who suffered from impotence for longer than 6 mois, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfil treatment compared to the placebo group.

Erections were improved in 72% of the Viagra group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mg. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates.

Vardenafil’s indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) et tadalafil (Cialis). Sildenafil Citrate is solely active in relaxing muscles and increasing blood flow to the heart, lungs and penis due to PDE-5, yet vasodilation is not increased in other parts of the body.

Application:

Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH).

La particularité pharmacologique du tadalafil réside dans sa demi-vie plus longue. (17.50 heures) – par rapport au sildénafil (4.0–5,0 heures) et vardénafil (4.0–5,0 heures) – ce qui entraîne une durée d’action plus longue, et donc en partie responsable de “La pilule du week-end” sobriquet. En outre, la demi-vie plus longue constitue la base des recherches actuelles sur l’utilisation thérapeutique quotidienne du tadalafil pour soulager l’hypertension artérielle pulmonaire.. Le sildénafil est approuvé dans plusieurs régions du monde comme traitement trois fois par jour contre l'hypertension artérielle pulmonaire..

Sildenafil citrate 50 mg is the recommended starting dose for men with erectile dysfunction (ED); toutefois, most men are later titrated to sildenafil 100 mg for improved efficacy.

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