Bromhydrate de dextrométhorphane de stéroïdes de perte de poids de sécurité pour la médecine de toux
Dextrométhorphane La description:
Dextromethorphan is the hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
Bromhydrate de dextrométhorphane monohydraté, in its pure form is a white powder that is most commonly used as a cough suppressant drug and is an active ingredient in most cough medicines. It is also used in a range of other medicines, from psychological to pain relief applications. It comes in several forms, either as a syrup, lozenge, spray, or tablet. Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices per 21CFR part 211 in FDA registered and inspected facilities.
Dextrométhorphane spécification:
Article |
Standard |
Résultat |
Apparence: |
White Crystalline Odorless |
White Crystalline Odorless |
Essai: |
99.9% Min |
99.95% |
Perte au séchage: |
12.00%Max |
10.02% |
Creatinine: |
80ppm |
Conformed |
Dicyandiamide |
20ppm Max |
Conformed |
Dihydrotriazines |
Négatif |
Conformed |
Métaux lourds(Pb) |
10ppm Max |
Conformed |
Cadmium |
Négatif |
Conformed |
Mercure: |
1ppm Max |
Conformed |
As |
1ppm Max |
0.03% |
Résidus à l'allumage: |
0.1% Max |
Conformed |
Nombre total de plaques: |
10cfu/gm Max |
Conformed |
Coli form |
Négatif |
Conformed |
E. Coli & Salmonelle: |
Négatif |
Conformed |
Yeast & Mould |
Négatif |
Conformed |
Solution |
Clear and Colorless |
Conformed |
Dextromethorphan Applications:
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
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