Pain Reducing Local Anesthetic Drugs Tetracaine Powder for Analgesic
Détail rapide
| Nom du produit |
Tétracaïne |
| Alias |
Amethocaine; Pontocaine; Dicaine; Laudocaine |
| CAS Registry Number |
94-24-6 |
| Einec Non |
202-316-6 |
| Formule moléculaire |
C15H24N2O2 |
| Masse moléculaire |
264.36 |
| Pureté |
99% |
| Classe |
Qualité pharmaceutique |
| Apparence |
white crytalline powder |
La description:
Tétracaïne, also known as amethocaine, is a local anesthetic used to numb the eyes, nose, or throat. Tetracaine may also be used before starting an intravenous to decrease pain from the procedure. Typically it is applied as a liquid to the area. Onset of effects when used in the eyes is within 30 seconds and last for less than 15 minutes.
Tetracaine was patented in 1930 and came into medical use in 1941. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 1.34 à 1.63 USD per 10 ml bottle. In the United Kingdom the eye drops cost the NHS about 0.49 pounds per dose.
Tetracaine Application
(1).In biomedical research, tetracaine is used to alter the function of the calcium release pathway (Lannottine receptor), which controls the release of calcium from intracellular stores. Dicaine is an allosteric blocker for channel function. At low concentrations, tetracaine causes initial inhibition of spontaneous calcium release events, whereas at high concentrations, tetracaine is completely released.
(2).Dinkaine is T in Tac, 5 à 12% tetracaine, 5M (countless), half (0.5 ‰) ou 0.05% (1 in 2000), 4% ou 10% of the salt used for ENT surgery Acid salts, and emergency departments that require rapid surface numbness, especially when children are injured in the eyes, ears or other sensitive parts.
(3).Tetracaine is synthesized from 4-butylaminobenzoic acid. The esterification reaction is carried out by acid catalysis to form ethyl ester. The base-catalyzed transesterification is achieved by boiling ethyl 4-butylaminobenzoic acid with an excess of 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Directeur commercial