IGF-1 LR3 [mg/flacon] CAS: 946870-92-4 Promouvoir une livraison efficace et sûre de la croissance musculaire

Renforcement musculaire IGF-1 LR3 [mg/flacon] CAS: 946870-92-4 Promouvoir une livraison efficace et sûre de la croissance musculaire

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IGF-1 LR3, également connu sous le nom de Long-Arginine-3-IGF-1, est un analogue de l'IGF-1 humain qui a été modifié pour inclure un 13 amino acid N-terminus extension and the substitution of Arginine for Glutamic Acid at position 3. As a result of these modifications, IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses an increased half-life due to lowered affinity for binding to the Insulin-Like Growth Factor-Binding Proteins (IGFBPs). IGF-1 LR3 retains the ability to bind agonistically to the IGF-1 receptor with improved metabolic stability, relative to IGF-1. The supplementation of mammalian cell cultures with Long R3 IGF-1 at a much lower concentration results in more highly elevated productivity than with standard concentrations of insulin and/or standard IGF-1. IGF-1 LR3 is more able to stimulate the type 1 IGF receptor and thus induce a higher level of activation of intracellular signaling, which is responsible for promoting cell proliferation and the inhibition of apoptosis.