Female Hormone 99% Oestradiol 17-Heptanoate CAS 4956-37-0 Estradiol Enanthate Raw Steroid Powder

MF:C25H36O3

MW:384.55

EINECS:225-599-8

Synonyms:oestradiol 17-heptanoate;1,3,5(10)-ESTRATRIEN-3,17BETA-DIOL 17-ENANTHATE;17BETA-ESTRADIOL ENANTHATE;17BETA-ESTRADIOL HEPTANOATE;17-BETA-ESTRADIOL 17-ENANTHATE;17-BETA-ESTRADIOL 17-HEPTANOATE;3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 17-ENANTHATE;estra-1,3,5(10)-triene-3,17b-diol 17-heptanoate

Melting point:94-96°

λmax286nm(EtOH)(lit.)

Merck 14,3703

Symbol(GHS)

COA

Description

Estradiol enanthate (INN, USAN), or estradiol enantate, is a synthetic ester, specifically the 17-heptanoyl ester, of the natural estrogen, estradiol. It is marketed under the brand names Anafertin, Deladroxate, Perlutan, and Topasel, which are combination formulations of estradiol enanthate and dihydroxyprogesterone acetophenide, as a once-monthly injectable hormonal contraceptive in Spain and Latin America, and has been used as such since at least the mid-1960s.

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο? (oistros, literally meaning “verve or inspiration”) and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations.Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.

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