White Powder Hexadecadrol Dxm Steroids Dexamethasones CASO:50-02-2 for Anti Inflammatory
Dexamethasone Basic Overview :
Dexamethaslo
CASO: 50-02-2
EINECS: 200-003-9
Calidad estandar: Bp/USP/EP
MF: C22H29FO5
MW: 392.46
Densidad: 1.32g/cm3
Punto de fusion: 255-264ºC
Punto de ebullición: 568.2º C at 760 mmHg
punto de inflamabilidad: 297.5ºC
Refractive index: 76 ° (C=1, Dioxane)
Vapour pressure: 2.81E-15mmHg at 25º C
Solubilidad: 10 mg/100 mL (25ºC)
Uso: Dexamethaslo and other sugar cortical hormone, has anti-inflammatory, anti-endotoxin, suppress the immune, resistance to shock and to enhance the pharmacological effects, such as the stress response, so it is widely applied in the treatment of many diseases in all the subjects, such as autoimmune diseases, allergy, inflammation, asthma and skin and eye disease.
Dexamethasone Descripción :
Dexamethaslo is a synthetic corticosteroid with approximately 25 times the anti-inflammatory potency of naturally occurring cortisol. The IUPAC Name of it is (8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl6,7,8,11,12,14,15, octahydrocyclopenta[a]phenanthren-3-one. Dexamethaslo commonly is used in both small- and large-animal veterinary medicine. It may be given by injection, inhalation orally or topically. Preparations for topical use may include other active ingredients such as antibiotics, antifungals or miticides.
Application of Dexamethaslo:
Dexamethaslo wide range of applications, the role of strong, significantly, is commonly used corticosteroids, in the rescue of allergic diseases, shock, and other severe acute endocrine crisis have played a key role, is indispensable clinical drugs. Dexamethasone anti-inflammatory effects and control skin allergy stronger than prednisone, its anti-inflammatory activity equivalent to 0.75mg 5mg prednisone, skin allergies better. For status asthmaticus critical situation of the disease, it may be a good short-term high-dose intravenous dexamethasone effects, intravenous infusion every 5 ~ 20mg, 4 ~ 6h can be repeated dosing, reduction after 48 ~ 72h, 5 ~ 7 days withdrawal. Patients with cerebral edema due to various reasons can be given for the first time 10mg intravenous injection. Every 4 a 6 hours after intramuscular injection of 2 ~ 4mg, generally can be alleviated within 24h, 48 ~ 72h reductions, 7 days withdrawal.
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