Vardenafil de la serie cruda del polvo del aumento del sexo para la disfunción eréctil masculina
Descripción:
Vardenafil is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil’s indications and contra-indications are the same as with other PDE5 inhibitors. The difference between the vardenafil molecule and is a nitrogen atom’s position and the change of sildenafil’s piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both and vardenafil. Vardenafil’s relatively short effective time is comparable to but somewhat longer than sildenafil’s. Vardenafil is a centrally-acting phosphodiesterase 5 inhibitor that is clinically used to treat erectile dysfunction. Vardenafil also exhibits antioxidative and antihypertensive activities and shows some potential for synergistic chemotherapeutic ability through its modulation of cGMP- NO signaling. This compound increases expression of NO and eNOS as well as activity of superoxide dismutase, decreasing oxidative stress, pulmonary vascular resistance, and right ventricular hypertrophy and increasing cardiac output in animal models of pulmonary arterial hypertension. Vardenafil decreases proteinuria and glomerular damage in animal models of diabetic nephropathy-induced cGMP pathway dysfunction. In cellular models, vardenafil decreases secretion of IL-8 and expression of oxidative LDLR, suggesting potential benefit in the treatment of benign prostatic hyperplasia/low urinary tract syndrome.
Solicitud:
Más allá de sus indicaciones para la disfunción eréctil, Vardenafil puede ser eficaz en el tratamiento de la eyaculación precoz., where it may significantly increase the time from vaginal penetration to ejaculation.Vardenafil, como con todos los inhibidores de la PDE5, no debe ser utilizado por hombres que toman medicamentos con nitrato, porque combinarlos con vardenafilo podría provocar hipotensión potencialmente mortal (presión arterial baja).Más lejos, Vardenafil provoca un alargamiento del intervalo QT. Por lo tanto, no debe ser tomado por hombres que estén tomando otros medicamentos que afecten el intervalo QT. (como la amiodarona).Vardenafil is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil’s indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to citrate and Tadalafil. The difference between the Vardenafil molecule and citrate is that a nitrogen atom has different position and the change of piperazine ring methyl group to an ethyl group.Tadalafil is structurally different from both and Vardenafil. Vardenafil’s relatively short effective time is comparable to but somewhat lon ger than . Vardenafilo, como con todos los inhibidores de la PDE5, no debe ser utilizado por hombres que toman medicamentos con nitrato, because combining them with Vardenafil might provoke potentially life-threatening hypotension .
Lab Test Result:
Elementos de prueba |
Especificación |
Resultados |
Apariencia |
White to off-White Crystalline Powder |
Polvo cristalino blanco |
Punto de fusion |
214-216° C |
214° C |
Related substances |
A single impurity≤1.0% |
0.11% |
Total impurities≤2.0% |
0.19% |
Pérdida por secado |
≤0,5% |
0.14% |
Ensayo |
97.0~103,0% |
99.3% |
Conclusión |
The specification conforms with Enterprise Standard |
Sex Drug Raw Powder
|
Sildenafil Citrate (viagra) |
Vardenafilo |
Tadalafil (cialis) |
Vardenafil HCL |
|
Yohimbina HCL |
HCL |
Avanafil |