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1. PHYSICO-CHEMICAL PROPERTIES
1.1 Origin of the substance
Naturally-occuring anabolic steroids are synthesised in
the testis, ovary and adrenal gland from cholesterol via
pregnenolone. Synthetic anabolic steroids are based on the
principal male hormone testosterone, modified in one of three
ways:
alkylation of the 17-carbon
esterification of the 17-OH group
modification of the steroid nucleus
1.2 Estructura química
Nombre químico:
17beta-Hydroxy-17alpha-methylandrosta-1,4-dien-3-one.
Fórmula molecular: C20H28O2
Peso molecular: 300.4
2. USES
2.1 Indications
2.1.1 Indications
Anabolic agent; systemic
Anabolic steroid
Androstan derivative; esteroide anabólico
Estren derivative; esteroide anabólico
Other anabolic agent
Anabolic agent for systemic use; veterinary
Anabolic steroid; veterinary
Estren derivative; veterinary
2.1.2 Descripción
The only legitimate therapeutic indications for
anabolic steroids are:
(a) replacement of male sex steroids in men who have
androgen deficiency, for example as a result of loss
of both testes
(b) the treatment of certain rare forms of aplastic
anaemia which are or may be responsive to anabolic
andrógenos.
(C) the drugs have been used in certain countries to
counteract catabolic states, for example after major
trauma.
2.3 Contraindicaciones
Known or suspected cancer of the prostate or (in men)
breast.
Pregnancy or breast-feeding.
Known cardiovascular disease is a relative contraindication.
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