Hormone Peptides Bremelanotide PT-141

Hormone Peptides Bremelanotide PT-141

Basic Information:

PT-141 Product Name: PT-141
PT-141 CAS: 32780-32-8
PT-141 MF: C50H69N15O10
PT-141 MW: 1040.17736
PT-141 Appearance: polvo blanco
PT-141 Water Content(Karl Fischer): ≤ 5.0%
PT-141 Acetate Content(por HPLC): ≤ 15.0%
PT-141 Amino Acid Composition: ± 10% of theoretical
PT-141 Purity(por HPLC): ≥ 97.0%
PT-141 Single Impurity(por HPLC): ≤ 1.0%
PT-141 Peptide Content(by %N): ≥ 80%
PT-141 Assay(By Anhydrous, Acetic Acid-free): 95.0~105,0%
PT-141 Bacterial Endotoxins: ≤ 5EU/mg
PT-141 Grade: Pharmceutical Grade
PT-141 Storage: Sombreado, conservación confinada.

Descripción

PT-141 or Bremelanotide is the generic term for a peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 has a similar structure to Melanotan-II and is a synthetic analogue of alpha-Melanocyte stimulating hormone (α-MSH). Alpha-MSH is an endogenous peptide that has potential influence over lipid metabolism, appetite, and sexual libido. PT-141 is a potential remedy for the treatment of sexual dysfunction and studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.

PT-141 Usage

PT-141, bremelanotide is experimental and is used for the purpose of sexual arousal. It is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger. An example of findings among male rats is displayed below in an abstract from this Palatin study:

Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder).

Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.