Zhongshan Latterson Biotechnology Co., Limitado.

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Factory Price Pharmaceutical Intermediate Raw Powder Agomelatine / S20098 CAS 138112-76-2 For Anti-Depression

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Otros productos de venta caliente (Polvo crudo)
Número de modelo : 138112-76-2
Certificación : GMP, SGS , YO ASI 9001:2008 , COMESTIBLE SEGÚN LA LEY JUDÍA
Lugar de origen : porcelana
MOQ : Estanozolol semielaborado de la serie líquida de esteroides
Precio : Negociable ( Descuentos para pedidos grandes )
Términos de pago : Western Union, MoneyGram, Transferencia bancaria, Bitcoin
Capacidad de suministro : 100 kg/mes
El tiempo de entrega : Dentro de 7 Días laborables
detalles del empaque : Embalaje sigiloso y discreto
nombre del producto : Agomelatine
Otro nombre : S20098
Apariencia : Polvo blanco
CAS No. : 138112-76-2
Pureza : 99% Min
Método de envío : EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
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Factory Price Pharmaceutical Intermediate Raw Powder Agomelatine / S20098 CAS 138112-76-2 For Anti-Depression

Superioridad

Zhongshan Latterson Biotechnology Co., Limitado., es una empresa farmacéutica integral, que se especializó en tecnología biofarmacéutica sobre 7 años. La empresa está ubicada en la ciudad de Zhongshan, Provincia de Guangdong , porcelana.
Nuestra fábrica cubre un área de 33500 metros cuadrados, con un ambiente limpio y un diseño agradable. Hay varios talleres grandes o medianos y un centro de investigación y control de calidad con equipos avanzados.. En el presente, Nuestros principales productos son la serie de esteroides anabólicos., Serie de péptidos, Serie de anestésicos locales. Nuestros productos alcanzan el estándar avanzado del mercado nacional., muchos de los cuales alcanzan el estándar internacional, los certificados contienen: COMESTIBLE SEGÚN LA LEY JUDÍA , YO ASI 9001:2008 , GMP , SGS.

AGOMELATINE

CASO:138112-76-2

MF:C15H17NO2

MW:243.30098

Sinónimos:S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamida;S 20098;AGOMELATIN;Acetamide, NORTE-(2-(7-methoxy-1-naphthalenyl)ethyl)-;Unii-137R1N49ad;Valdoxan;AgoMelatine(S-20098,Valdoxan);Thymanax

Propiedades

Punto de fusion:107-109° C

temperatura de almacenamiento. -20° C Congelador

solubilidad DMSO: >50mg / mL

color white to off-white

Safety Information

Symbol(GHS)

Abstracto

Agomelatine should be started at the recommended dose of 25mg (one tablet) a day, which MUST BE TAKEN AT BED-TIME.

After two weeks, if there has been no improvement, increasing the dose to 50mg (two tablets) at bed-time should be considered.

Here’s a summary of the key points about Agomelatine.

Agomelatine is a new antidepressant that works in a different way from other antidepressants
Agomelatine is particularly helpful if you have problems sleeping as part of your depression
The usual dose is one 25mg tabletit MUST be taken at bed-time
Agomelatine has few side effectsthe only one that happened more frequently than with a placebo (a dummy pill) was dizziness
Agomelatine should be used with caution in people over the age of 65 años, and never in people with Alzheimer’s disease
Agomelatine can affect the liver, entonces, for the time being at least, you may be asked to have a blood test when taking it

Medical Uses

Agomelatine is indicated for the treatment of major depressive episodes in adults.Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten short-term double-blind placebo-controlled studies.Two were consideredfailedtrials, as comparators of established efficacy failed to differentiate from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies.The maintenance of antidepressant efficacy was demonstrated in a relapse prevention study.

Results of the meta-analysis of three positive, randomized, doble ciego, placebo controlled studies in 357 patients treated with agomelatine and 360 patients treated with placebo show that agomelatine is effective in treating severe depression. Its antidepressant effect is greater for more severe depression. In patients with a greater baseline score (>30 on HAMD17 scale), the agomelatine-placebo difference was of 4.53 points.Controlled studies in humans have shown that agomelatine is at least as effective as the SSRI antidepressants paroxetine, sertraline, escitalopram, venlafaxine and fluoxetine in the treatment of major depression.

A large meta-analysis of 20 trials with 7460 participants found agomelatine to be as effective as standard antidepressants.

A small open-label study has suggested efficacy in the treatment of atypical and melancholic depression.Well-designed clinical trials have demonstrated efficacy in the treatment of anxious depression.Agomelatine’s onset of action has been reported to occur as early as the first week of treatment.

How does it work

Valdoxan tablets contain the active ingredient agomelatine, which is a type of medicine called an antidepressant. It is used to treat depression.

Agomelatine acts on the melatonin and serotonin receptors in the brain.

Melatonin is a hormone made by the pineal gland, a structure in the brain. It is normally released soon after it starts to get dark. The amount produced then increases until about four am, before dropping off again. Melatonin is linked with the control of circadian rhythms and promoting sleep. It works by acting on melatonin receptors in the brain.

Agomelatine mimics the action of melatonin and helps to re-synchronise the body’s circadian rhythms. These include mood, anxiety, appetite, body temperature and sleep/wake cycles. These circadian rhythms, particularly sleep cycles, are severely disturbed in people with depression. Agomelatine’s main action is to improve the onset and quality of sleep and this in turn has an antidepressant effect.

Agomelatine also helps to improve mood in depression by increasing noradrenaline and dopamine release in the brain. These are natural chemicals called neurotransmitters that are involved, amongst other things, in regulating mood.

Uso

1) los (S)-enantiomer of the ethyl analog of Piracetam. Used as an anticonvulsant.

2) los (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.

3) A compound which inhibits burst firing without affecting normal neuronal excitability

4) Used as adjunctive therapy in the treatment of partial onset seizures in adults and children 4 years of age and older with epilepsy.

Nuestro servicio

1.100% La política de reenvío es nuestro negocio básico. Reenvío del 100% inmediatamente si su paquete permanece en Aduana por 4 días y no se actualiza.
2.Reembolso total por 15 días de insatisfacción con la calidad.
3.Podemos proporcionar muestras gratis..
4.Tenemos un embalaje especial ,Se puede pasar fácilmente por la aduana.Será más seguro..
5.Nuestra empresa tiene una cooperación a largo plazo con DHL.EMS.Fedex y así sucesivamente. Se puede enviar a su mano más rápidamente. La foto del paquete debe ofrecerse dentro de las 12 horas posteriores a la recepción de su pago de esteroides.
6.Si tienes la oportunidad de venir a China. Puedo mostrarte nuestro laboratorio.
7.Nuestra empresa tiene WU, MG, TT, y formas de pago de Bitcoin por adelantado. 95% por el costo de los péptidos al principio por pedido, el resto nos lo puede ofrecer en su próximo pedido;

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