99% Estrogens Series Pharmaceutical Raw Materials Progestogen Megestrol Acetate

Superioridad

Zhongshan Latterson Biotechnology Co., Limitado., es una empresa farmacéutica integral, que se especializó en tecnología biofarmacéutica sobre 7 años. La empresa está ubicada en la ciudad de Zhongshan, Provincia de Guangdong , porcelana.
Nuestra fábrica cubre un área de 33500 metros cuadrados, con un ambiente limpio y un diseño agradable. Hay varios talleres grandes o medianos y un centro de investigación y control de calidad con equipos avanzados.. En el presente, Nuestros principales productos son la serie de esteroides anabólicos., Serie de péptidos, Serie de anestésicos locales. Nuestros productos alcanzan el estándar avanzado del mercado nacional., muchos de los cuales alcanzan el estándar internacional, los certificados contienen: COMESTIBLE SEGÚN LA LEY JUDÍA , YO ASI 9001:2008 , GMP , SGS.

Product Details:

Sinónimos: Nomegestrol Acetate; 17-hydroxy-6-methylpregna-4
Inchi: InChI=1/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23, 15(2)25)28-16(3)26/h12-13, 18-20H, 6-11H2, 1-5H3/t18-, 19+, 20+, 22-, 23+, 24+/m1/s1
No CAS.: 595-33-5
ECNECS No.: 209-864-5
MF: C24H32O4
MW: 384.5
Pureza: 99%
Densidad: 1.15g/cm3
Punto de fusion: 214ºC
Punto de ebullición: 507.1° Cat760mmHg
Refractive Index: 11 ° (C=2, CHCl3)
Flash Point: 218.5°C
Apariencia: White or light yellow crystalline powder
Calificación: As
Almacenamiento: Sombreado, conservación confinada

Descripción:

Megestrol acetate, also known as 17α -acetoxy-6-dehydro-6-methylprogesterone, and sometimes abbreviated as MGA or MA, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects. Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.

Solicitud:

Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.

In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
Dosis: Megestrol acetate is available as 5 mg, 20 mg and 40 mg tablets and in oral suspensions of 125 mg/ml and 40 mg / ml. It is used at a dose of 5 mg in combination with an estrogen for contraception. Appetite stimulation is achieved with doses ranging from 400 mg to 800 mg al día. Doses used to treat cancer usually range from 40 mg to 320 mg.

Uso:

1. Megestrol is used mainly to treat breast cancer. It is also sometimes used to treat endometrial cancer and prostate cancer.
2. Megestrol can be used to treat metastatic or recurrent breast cancerafter tamoxifen treatment. It can also be used when tamoxifen is not effective.
3. Megestrol can be used as an appetite stimulant for people experiencing loss of appetite and weight loss because of advanced cancer.
4. A synthetic progestational agent, commonly used for estrus control in dogs and cats and also in the treatment of behavioral abnormalities and a variety of inflammatory skin diseases, including miliary dermatitis and eosinophilic granuloma.
5. Suppress growth of progestin-sensitive breast and endometrial tumors by inhibiting pituitary and adrenal function.

Megestrol acetate in liquid suspension form is approved to treat the following conditions in patients with AIDS:
Anorexia (pérdida de apetito).
Cachexia (weakness and loss of weight and muscle).
Megestrol acetate is also being studied in the treatment of anorexia and cachexia incancer and other conditions.

COA: