Dutasteride/Avodart CAS 164656-23-9 For Treating Hair loss Without Side Effect
Quick Details :
Dutasteride (Avodart)
English Synonyms: (5alpha,17beta)-n-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide;DUTASTERIDE;GG-745, GI-198745,;5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4- Aza -androst-1-ene-17-carboxamide;Duagen;(5a,17)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide;Avodart;GI 198745
CAS NO.: 164656-23-9
Assay: 99%
Molecular Formula:C27H30F6N2O2
Molecular Weight:528.53
Packing:1kg/tin/foil bag
Standard: Enterprise/USP
Appearance: White or almost white crystalline powder
Usage: Prostate enlargement, male pattern hair loss, seborrheic alopecia, hereditary hair loss
Application:
This class of medications increases rates of erectile dysfunction (with between 5% and 9% developing problems after starting their use). This is linked to lower quality of life and can cause stress in relationships. There is also an association with lowered sexual desire. It has been reported that these adverse sexual side effects may persist even after discontinuation of the drug. The FDA has added a warning to dutasteride about an increased risk of high-grade prostate cancer.
While the potential for positive, negative or neutral changes to the potential risk of developing prostate cancer with dutasteride has not been established, evidence has suggested it may temporarily reduce the growth and prevalence of benign prostate tumors, but could also mask the early detection of prostate cancer.
Dutasteride /Avodart COA:
Test Items |
Specification |
Test Results |
Description |
White or almost white powder |
Complies |
Identification |
Meet the requirements |
Complies |
Loss on drying |
≤0.5% |
0.2% |
Melting range |
246°~252° |
246¡æ~248¡æ |
Heavy metals |
≤20ppm |
Complies |
Residue on ignition |
≤0.1% |
Complies |
Related substances |
Biggest Impurities≤0.5% |
0.36% |
|
Total Impurity≤1.0% |
0.7% |
Assay |
97.0%~103.0% |
99.3% |
Conclusion |
Complies with In-house Standard |