MF:C14H10Cl2NNaO2
MW:318.13
EINECS:239-346-4
Synonyms:N-(2,6-Dichlorophenyl)-o-aminophenylacetic acid sodium salt;OOTHECA MANTIDIS;Diclofenac SodiuM EC pellets 32%;Diclofenac SodiuM SR pellets 32%;Diclofenac Sodium (200 mg);DelphiMix;Diacron;Naclof
Description
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation.
Diclofenac is used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis. The Cataflam brand of this medicine is also used to treat menstrual cramps.
Diclofenac powder (Cambia) is used to treat a migraine headache attack. Cambia will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
diclofenac Uses
Diclofenac is used to relieve pain, swelling (inflammation), and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).
If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section.
Diclofenac sodium Basic information |
Product Name: |
Diclofenac sodium |
Synonyms: |
(o-(2,6-dichloroanilino)phenyl)aceticacidmonosodiumsalt;(o-(2,6-dichloroanilino)phenyl)aceticacidsodiumsalt;2-((2,6-dichlorophenyl)amino)-benzeneaceticacimonosodiumsalt;2-[(2,6-Dichlorophenyl)amino]benzeneaceticacidsodiumslat;2[(2,6-dichlorophenyl)amino]-benzeneaceticacimonosodium;diclophenacsodium;gp45840;huma-difenac |
CAS: |
15307-79-6 |
MF: |
C14H10Cl2NNaO2 |
MW: |
318.13 |
EINECS: |
239-346-4 |
Product Categories: |
Active Pharmaceutical Ingredients;Organics;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;API’s;Lipid signaling;Amines;Aromatics;Heterocycles;VOLATREN;Other APIs |
Mol File: |
15307-79-6.mol |
|
|
Diclofenac sodium Chemical Properties |
mp |
288-290°C |
storage temp. |
-20°C Freezer |
solubility |
H2O: 50 mg/mL |
Merck |
3081 |
Stability: |
Stable. |
CAS DataBase Reference |
15307-79-6(CAS DataBase Reference) |
Hazard Codes |
T,Xi |
Risk Statements |
25-36/37/38 |
Safety Statements |
22-36/37-45-36-26 |
RIDADR |
UN 2811 6.1/PG 3 |
WGK Germany |
3 |
RTECS |
AG6330000 |
HazardClass |
6.1(b) |
PackingGroup |
III |
ProviderLanguage
|
2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt |
English |
SigmaAldrich |
English |
|
Diclofenac sodium Usage And Synthesis |
Chemical Properties |
Off-White Crystalline Solid |
Usage |
A nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor. |
Usage |
A nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor |
|
Diclofenac sodium Preparation Products And Raw materials |
Raw materials |
Etanol–>Aniline–>Chloroacetyl chloride–>2-Chlorobenzoic acid–>2-Chlorotoluene–>2,6-Dichlorophenol–>2,5-Dichloroaniline |
How to use Diclofenac sodium
Read the Medication Guide provided by your pharmacist before you start using diclofenac and each time you get a refill. If you have any questions, ask your doctor or pharmacist…
Diclofenac dosing information
Usual Adult Dose for Osteoarthritis:
Diclofenac free acid capsules: 35 mg orally 3 times a day
Diclofenac potassium immediate-release tablets: 50 mg orally 2 or 3 times a day
Diclofenac sodium enteric-coated tablets: 50 mg orally 2 or 3 times a day or 75 mg orally 2 times a day
Maximum dose: 150 mg daily
Diclofenac sodium extended-release tablets: 100 mg orally once a day
Use: For the relief of signs and symptoms of osteoarthritis.
Usual Adult Dose for Ankylosing Spondylitis:
Diclofenac sodium enteric-coated and delayed-release tablets: 25 mg orally 4 times a day. An additional 25 mg dose may be administered at bedtime, if necessary
Maximum dose: 125 mg per day
Use: For acute or long-term use in the relief of signs and symptoms of ankylosing spondylitis.
Usual Adult Dose for Dysmenorrhea:
Diclofenac potassium immediate-release tablets: 50 mg orally 3 times a day
Comments: An initial dose of 100 mg orally followed by 50 mg oral doses may provide better relief for some patients; initiate treatment upon appearance of the first symptoms and continue for a few days.
Use: For the relief of signs and symptoms of primary dysmenorrhea.
Usual Adult Dose for Rheumatoid Arthritis:
Diclofenac potassium immediate-release tablets: 50 mg orally 3 or 4 times a day
Diclofenac sodium enteric-coated and delayed-release tablets: 50 mg orally 3 to 4 times a day or 75 mg orally twice a day
Maximum dose: 225 mg daily
Diclofenac sodium extended-release tablets: 100 mg orally once a day
Maximum dose: 100 mg orally 2 times a day; this would be for the rare patient in whom the benefits outweigh the clinical risks.
For the relief of signs and symptoms of rheumatoid arthritis
Usual Adult Dose for Migraine:
Diclofenac potassium for oral solution packets: 50 mg (1 packet) orally once
Comments: This drug is not indicated for the prophylactic therapy of migraine or for use in cluster headaches; the safety and efficacy of a second dose has not been established.Use: For acute treatment of migraine with or without aura.Usual Adult Dose for Pain:Diclofenac potassium liquid-filled capsules: 25 mg orally 4 times a day Diclofenac free acid capsules: 18 mg or 35 mg orally 3 times a day
Diclofenac potassium immediate-release tablets: 50 mg orally 3 times a day; an initial dose of 100 mg orally followed by 50 mg oral doses may provide better relief in some patients.
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