Stimulating Drug Colorless Transparent Prismatic L- Menthol CAS 2216-51-5

Beschreibung

Menthol is an organic compound made synthetically or obtained from corn mint, peppermint, or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above.

Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minorthroat irritation. Menthol also acts as a weak kappa opioid receptor agonist.

Anwendungen

As an antipruritic to reduce itching.

As a penetration enhancer in transdermal drug delivery.

As a smoking tobacco additive in some cigarette brands, for flavor, and to reduce throat and sinus irritation caused by smoking. Menthol also increases nicotine receptor density,increasing the addictive potential of tobacco products

As a pesticide against tracheal mites of honey bees.

As an antispasmodic and smooth muscle relaxant in upper gastrointestinal endoscopy

In organic chemistry, menthol is used as a chiral auxiliary in asymmetric synthesis. For example,sulfinate esters made from sulfinyl chlorides and menthol can be used to make enantiomerically pure sulfoxides by reaction with organolithium reagents or Grignard reagents. Menthol reacts with chiral carboxylic acids to give diastereomic menthyl esters, which are useful for chiral resolution.

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