Powerful Local Anesthetic Drugs Procaine HCl Pharmaceutical Raw Materials
Produktprofil
Produktname: Procain HCl
Alias: Procainhydrochlorid; Aminocaine; Anadolor; Atoxicocaine;
CAS-Registernummer: 51-05-8
EINECS: 200-077-2
Molekularformel: C13H21ClN2O2
Molekulargewicht: 272.77
Assay: 99%
Lagerung: Schattierung, eingeschränkte Erhaltung
Aussehen: weißes kristallines Pulver
Einführung
Procaine HCl is a local anesthetic drug of the amino ester group. Es wird hauptsächlich zur Schmerzlinderung bei der intramuskulären Injektion von Penicillin eingesetzt, und es wird auch in der Zahnheilkunde verwendet. Aufgrund der Allgegenwärtigkeit des Handelsnamens Novocain, in some regions procaine is referred to generically as novocaine. Es wirkt hauptsächlich als Natriumkanalblocker. Heutzutage wird es aufgrund seiner sympatholytischen Wirkung in einigen Ländern therapeutisch eingesetzt, Antiphlogistikum, Durchblutungssteigerung, und stimmungsaufhellende Wirkung.
Procaine Hydrochloride Applications :
Procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.
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