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Schnelle Details:
| Produktname |
Dextromethorphan-Hydrobromid-Monohydrat |
| Anderer Name |
DMHM;D-Methorphan hydrobromide monohydrate |
| FALL |
125-69-9 |
| MF |
C18H28BrNO2 |
| MW; |
370.32 |
|
|
| Assay |
99% |
| Aussehen: |
weißes Puder |
| Verwendung |
An antitussive drug |
Beschreibung:
Dextromethorphan Hydrobromide is the hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
Anwendung:
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist.. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
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