Zhongshan Latterson Biotechnology Co., GmbH., ist ein umfassendes Pharmaunternehmen, die sich auf biopharmazeutische Technologie spezialisiert haben 7 Jahre. Das Unternehmen befindet sich in der Stadt Zhongshan, Provinz Guangdong , China.
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FALL:846589-98-8
MF:C11H15Cl2N
Synonyme:(R)-1H-3-BENZAZEPINE,8-CHLORO-2,3,4,5-TETRAHYDRO-1-METHYL-,HYDROCHLORIDE;LORCASERIN HCL;Lorcaserin hydrochloride;(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride;(1R)-8-chloro-1-Methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;R Lorcaserin hydrochloride;lorcaserin hydrochloride (APD-356);(R)-8-Chloro-1-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride
Beschreibung:
Belviq(Lorcaserin hydrochloride) is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight? adults with a weight-related medical problem, or obese adults, lose weight and keep it off. It is not known if BELVIQ when taken with other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is not known if BELVIQ changes your risk of heart problems, stroke, or death due to heart problems or stroke.
Anwendungen:
Belviq is a serotonin 2C receptor agonist. It hasbeen shown to decrease food consumption and promote satiety by selectivelyactivating serotonin 2C receptors in the brain.
Belviq is specifically indicated as an adjunct to a reduced-calorie diet andincreased physical activity for chronic weight management in clinically obeseadults (BMI of 30 kg/m2 or greater) and overweight adults (BMI of 27 kg/m2 orgreater) with at least one weight-related comorbid condition.
Belviq is supplied as a tablet designed for oral administration. The recommendeddose is one 10mg tablet twice daily. Use of Belviq should be discontinued if 5%weight loss is not achieved by week 12 of treatment.
Testing report of Lorcaserin Hydrochloride :
|
PROBEARTIKEL |
SPEZIFIKATION |
ERGEBNISSE |
|
| Beschreibung |
weißes Puder |
Entspricht |
|
| Moisture |
≤1% |
0.34% |
|
| Dichte |
1.073 |
1.075 |
|
| Assay |
≥98,5 % |
99.31% |
|
| Schwermetall |
≤10ppm |
Entspricht |
|
| LK |
Acetone 0.5% |
Entspricht |
| Ethyl acetate 0.5% |
| Dichloromethane 0.06% |
| Fazit |
Die Spezifikation entspricht dem Unternehmensstandard |
Lorcaserin, currently marketed under the trade name Belviq and previously Lorqess during development,is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic.
Lorcaserin is used long term for weight loss in those who are obese.BELVIQ is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off.
Lorcaserin HCl is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off. It is not known if Lorcaserin HCl when taken with other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is not known if Lorcaserin HCl changes your risk of heart problems, stroke, or death due to heart problems or stroke.
lorcaserin hydrochloride is a serotonin 2C receptor agonist. It hasbeen shown to decrease food consumption and promote SA tiety by selectivelyactivating serotonin 2C receptors in the brain.Lorcaserin HCl is specifically indicated as an adjunct to a reduced-calorie diet andincreased physical activity for chronic weight management in clinically obeseadults (BMI of 30kg/m2 or greater) and overweight adults (BMI of 27kg/m2 orgreater) with at least one weight-related comorbid condition.
Lorcaserin HCl is supplied as a tablet designed for oral administration. The recommendeddose is one 10mg tablet twice daily. Use of Lorcaserin HCl should be discontinued if 5%weight loss is not achieved by week 12 of treatment.
Lorcaserin VS Orlistat:
Lorcaserin is a selective 5-HT2C receptor agonist,and in vitro testing of the drug showed reasonable selectivity for 5-HT2C over other related targets. 5-HT2C receptors are located almost exclusively in the brain. The activation of 5-HT2C receptors in the hypothalamus is supposed to activate proopiomelanocortin (POMC) production and consequently promote weight loss through satiety.The safety and effectiveness was tested in the 3 clinical trials which nearly 8000 overweight or obese participants were involved.
Orlistat works by inhibiting gastric and pancreatic lipases, the enzymes that break down triglycerides in the intestine. When lipase activity is blocked, triglycerides from the diet are not hydrolyzed into absorbable free fatty acids, and instead are excreted unchanged. Only trace amounts of orlistat are absorbed systemically; the primary effect is local lipase inhibition within the GI tract after an oral dose. The primary route of elimination is through the feces. But for a part of stubborn obesity who get good appetite, the treatment effect is not ideal.
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