99.8 % Pharmaceutical Grade Raw Materials Promethazine HCL
Überlegenheit
Zhongshan Latterson Biotechnology Co., GmbH., ist ein umfassendes Pharmaunternehmen, die sich auf biopharmazeutische Technologie spezialisiert haben 7 Jahre. Das Unternehmen befindet sich in der Stadt Zhongshan, Provinz Guangdong , China.
Unsere Fabrik umfasst eine Fläche von 33500 Quadratmeter, mit sauberer Umgebung und schönem Layout. Es gibt mehrere große oder mittlere Werkstätten und ein QS- und Forschungszentrum mit fortschrittlicher Ausrüstung. Derzeit, Unsere Hauptprodukte sind anabole Steroide, Peptid-Serie, Lokalanästhesie-Serie. Unsere Produkte erreichen den fortgeschrittenen Standard des heimischen Marktes, viele davon erreichen den internationalen Standard, Zertifikate enthalten: KOSCHER , ISO 9001:2008 , GMP , SGS.
Product Details:
Produktname |
Promethazine hydrochlorine |
Anderer Name |
Promethazine HCl |
Chemcial Name |
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine |
FALL |
58-33-3 |
MF |
C17H21ClN2S |
MW |
320.88 |
EINECS |
200-375-2 |
Assay |
99.8% |
Aussehen |
weißes Puder |
urpose |
This product is used for skin and mucosa irritation, allergic rhinitis,
asthma, food allergies, skin scratch disease, motion sickness, airsickness etc.. |
Beschreibung:
Promethazine hydrochloride is a phenothiazine used to treat or prevent nausea and vomiting caused by anesthesia or surgery, certain types of allergic reactions, pain caused by surgery or childbirth, and to sedate patients before surgery or medical procedures. Promethazine injection is usually given when a person cannot take the medication orally (by mouth). Promethazine hydrochloride is available in generic form. Promethazine hydrochloride suppositories (Brand Names: Phenadoz, Promethegan) is a phenothiazine that works by changing the actions of chemicals in your brain, and also acts as an antihistamine, used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. Promethazine hydrochloride suppositories is also used to prevent motion sickness, treat nausea and vomiting or pain after surgery, and as a sedative or sleep aid. Promethazine hydrochloride suppositories are available in generic form. Common side effects of promethazine hydrochloride suppositories include dizziness, drowsiness, sleepiness, restlessness, blurred vision, dry mouth, stuffy nose, ringing in the ears, Gewichtszunahme, swelling in hands or feet, impotence, trouble having an orgasm, or constipation.
Anwendung:
Antihistaminic, antiemetic, CNS depressant stool softener With aminophylline in the treatment of asthma For the treatment of allergic disorders, and nausea/vomiting.
Dubbed hibernation and injection for artificial hibernation. Perennial and seasonal allergic rhinitis Vasomotor rhinitis.Allergic conjunctivitis due to inhalant allergens and foods.Mild, uncomplicated allergic skin manifestations of urticaria and angioedema.
Amelioration of allergic reactions to blood or plasma. Dermographism. Anaphylactic reactions, as adjunctive therapy to epinephrine and other standard measures, after the acute manifestations have been controlled. Preoperative, postoperative, or obstetric sedation. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. Therapy adjunctive to meperidine or other analgesics for control of postoperative pain. Sedation in both children and adults, as well as relief of apprehension and production of light sleep from which the patient can be easily aroused. Active and prophylactic treatment of motion sickness. Antiemetic therapy in postoperative patients.
The dose of promethazine depends on the condition being treated. Typical doses range from 12.5 mg to 25 mg, and may be taken once daily or several times per day, as prescribed. Promethazine may interact with cold or allergy medicine, sedatives, narcotics, sleeping pills, muscle relaxers, medicine for seizures, Depression, lithium, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, blood pressure medications, blood thinners, bronchodilators, bladder or urinary medications, MAO inhibitors, medicines to treat Parkinson’s disease, restless leg syndrome, or pituitary gland tumor, medicines to treat stomach ulcer or irritable bowel syndrome. Many other medicines can interact with promethazine. Tell your doctor all medications and supplements you use. During pregnancy, promethazine should be used only if prescribed. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
Echtheitszertifikat:
Elemente der Analyse |
Spezifikation |
Ergebnisse |
description |
a white or faintly yellowish,kristallines Pulver |
a white crystalline powder |
solubility |
very soluble in water,freely soluble in chloroform and in ethanol(95%),practically insoluble in ether |
very soluble in water,freely soluble in chloroform and in ethanol(95%);practically insoluble in ether |
identification |
|
|
EIN. IR absorption spectrum |
the positions and relative sizes of the banks in the spectrum of the sample and reference spectrum shall be concordant |
the positions and relative sizes of the bands in the spectrum of the sample and reference spectrum are concordant |
B.by TLC |
It complies with the identification test for phenothiazines |
it complies with the identification test for phenothiazine |
C.Test with nitric acid |
forms orange colored solution and organge-red precipitate |
forms orange colored solution and organge-red precipitate |
D.test for chlorides |
shall comply the test |
complies with test for chlorides |
pH(10% w/v solution) |
4.0-5.0 |
4.31 |
related substances(von TLC) |
|
|
isopromethazine |
nicht mehr als 1.0% |
weniger als 1.0% |
other impurity |
nicht mehr als 0.5% |
weniger als 0.5% |
sulphated ash |
nicht mehr als 0.5% |
0.20% |
loss on drying at 105ºC |
nicht mehr als 0.5% |
0.20% |
Test(by potentiometric titration) |
98.5-101%(on anhydrous basis) |
100.0% |
Fazit |
Qualifiziert |
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