100% High Quality Emergency Contraception Drug Raw Powder
Überlegenheit
Zhongshan Latterson Biotechnology Co., GmbH., ist ein umfassendes Pharmaunternehmen, die sich auf biopharmazeutische Technologie spezialisiert haben 7 Jahre. Das Unternehmen befindet sich in der Stadt Zhongshan, Provinz Guangdong , China.
Unsere Fabrik umfasst eine Fläche von 33500 Quadratmeter, mit sauberer Umgebung und schönem Layout. Es gibt mehrere große oder mittlere Werkstätten und ein QS- und Forschungszentrum mit fortschrittlicher Ausrüstung. Derzeit, Unsere Hauptprodukte sind anabole Steroide, Peptid-Serie, Lokalanästhesie-Serie. Unsere Produkte erreichen den fortgeschrittenen Standard des heimischen Marktes, viele davon erreichen den internationalen Standard, Zertifikate enthalten: KOSCHER , ISO 9001:2008 , GMP , SGS.
Grundinformation:
Produktname: Levonorgestrel
Synonyme: 13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one;13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one;13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1;17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one;17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one;17-ethynyl-18-methyl-19-nortestosteron;17-ethynyl-18-methyl-19-nortestosterone;18-methyl-17-alpha-ethynyl-19-nortestosterone
FALL: 797-63-7
MF: C21H28O2
MW: 312.45
EINECS: 212-349-8
Melting point 206°C
alpha D20 -32.4° (c = 0.496 in CHCl3)
Lagertemperatur. 2-8° C.
appearance White Solid
Beschreibung:
Oral Contraceptive Levonorgestre, also called D-norgestre and left Kanok ketone, is known as the most widely used oral contraceptives currently. It is the optically active part of racemic norgestrel. With activity twice as strong as norethindrone, when the dose is reduced by half, its adverse reactions will reduce correspondingly. Besides it has rapid oral absorption that can reach the peak within 0.5~1h with t1/2 of 10~24 h, protein binding rate of 93% zu 95% and high bioavailability. It mainly distributed in liver, Niere, ovarian and uterine body’s organs and tissues, and its metabolites, mainly in the form of glucuronide and sulfate salts, excrete from the urine and feces. It combined with ethinyl estradiol to be short-acting oral contraceptives. Its biphasil and triphasil have fewer adverse reactions, and are more closer to women normal hormone secretion type. They can be used for emergency contraception even in post-coital contraception without protective measures or failed contraception (condom slippage or breakage, coitus out of control, rhythm miscalculation, usw.). As the triphasil reduces this product by 40%, there will be less adverse reactions. If Levonorgestrel`s dosage form is changed, it can also be used as a variety of long-acting contraceptives. Used as a short-acting oral contraceptives: From the 5th day of menstruation start taking compound levonorgestrel tablets, one tablet a day for 22 days without interruption, before bedtime. After serving so on the 5th day of the next menstruation, continue the medication. The users may have nausea, vomiting, Kopfschmerzen, breast fullness after serving, Akne, Gewichtszunahme, Depression, lowered HDL, breakthrough bleeding, amenorrhea, etc. Leber- und Nierenfunktionsstörung, breast lumps patients are prohibit taking it. Not suitable for use as regular birth control pills, reliable contraceptive measures should be taken to the next pre-menstrual after taking the drug. Women who smoke should not take it (due to easily complication of cardiovascular disease).
Uses Progestin drugs for irregular menstruation, functional uterine bleeding, endometriosis, etc.
Verwendung:
1. An emergency contraceptive. Levonorgestrel is safe, tolerated and effective in emergency contraception in woman
2. progestin
Anwendung:
1.Oral contraception
At low doses, levonorgestrel is used in monophasic and triphasic formulations of combined oral contraceptive pills, with available monophasic doses ranging from 100-250 μ G, and triphasic doses of 50 μ G/75 μ G/125 μ G.
At very low daily dose of 30 μ G, levonorgestrel is used in some progestogen only pill formulations.
2.Emergency contraception
Levonorgestrel is used in emergency contraceptive pills (ECPs), both in a combined Yuzpe regimen which includes estrogen, and as a levonorgestrel-only method. The levonorgestrel-only method uses levonorgestrel 1.5 mg (as a single dose or as two 0.75 Testosteronpropionat im mittleren Körper 12 hours apart) taken within 3 days of unprotected sex, with one study indicating that beginning as late as 120 Std (5 Tage) after intercourse could be effective.
3.Intrauterine system
Levonorgestrel is the active ingredient in the Mirena & Skyla (Jaydess) intrauterine system.
4.Contraceptive implants
Levonorgestrel is the active ingredient in Norplant and Jadelle.
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