CAS 1270138-41-4 NSI-189 For Improving Mood 99% Purity for sale Factory Supply
NSI-189 Certificate of Analysis:
Product name |
NSI-189 |
CAS No. |
1270138-40-3 |
Outer Packing |
|
Production date |
Feb. 7th. 2018 |
Shelf life |
Feb. 6th. 2021 |
Standard adopted |
in-house standard |
Items of analysis |
Specification |
Results |
Appearance |
Off-white powder |
Confrom |
Identification |
IR and HPLC spectrum shall conform to the standard sample |
conform |
Melting Point |
83ºC~86ºC |
84.3ºC~85.6ºC |
Loss on Drying |
Less than 0.5% |
0.29% |
Purity(On Dried Base,HPLC) |
NLT 99.5 % |
99.62% |
Total Impurity |
Less than 0.5% |
0.33% |
Residue On Ignition |
≤0.2% |
0.16% |
Heavy metal |
≤20ppm |
conform |
Conclusion |
Qualified |
NSI-189 Describtion :
NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer’s disease, and major depressive disorder (MDD).
NSI-189’s Method of Action:
Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from disease’s such as Alzheimer’s .
COA
Items of Analysis |
Requirements |
Results |
Appearance |
Off-white to white powder |
Conforms |
Loss on drying |
≤1.0% |
0.6% |
Heavy metal |
≤10ppm |
Conforms |
Water |
≤0.5% |
0.3% |
Purity(HPLC) |
≥99% |
99.47% |
Residue on ingnition |
≤0.3% |
0.05% |
Conclusion |
The product conforms to in House Standard |
Packing |
Pack in two layers plastic-bag. |
Storage |
Store in a well-closed place with constant low temperature and no direct sun light. |
Shelf life |
2 years when properly stored. |