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  • CAS 1270138-41-4 NSI-189 For Improving Mood 99% Purity for sale Factory Supply

    CATEGORY AND TAGS:
    Other Hot-Sale Products (Raw Powder)
    Certification: ISO9001, KOSHER, USP, GMP
    Model Number: 1270138-40-3
    Minimum Order Quantity: 10grams
    Delivery Time: 2~7 working days
    Payment Terms: T/T, , Western Union, MoneyGram, Bitcoin
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    • Specifications

    CAS 1270138-41-4 NSI-189 For Improving Mood 99% Purity for sale Factory Supply

    NSI-189 Certificate of Analysis:

    Product name NSI-189
    CAS No. 1270138-40-3 Outer Packing
    Production date Feb. 7th. 2018 Shelf life Feb. 6th. 2021
    Standard adopted in-house standard
    Items of analysis Specification Results
    Appearance Off-white powder Confrom
    Identification IR and HPLC spectrum shall conform to the standard sample conform
    Melting Point 83ºC~86ºC 84.3ºC~85.6ºC
    Loss on Drying Less than 0.5% 0.29%
    Purity(On Dried Base,HPLC) NLT 99.5 % 99.62%
    Total Impurity Less than 0.5% 0.33%
    Residue On Ignition ≤0.2% 0.16%
    Heavy metal ≤20ppm conform
    Conclusion Qualified

    NSI-189 Describtion :

    NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.

    The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer’s disease, and major depressive disorder (MDD).

    NSI-189’s Method of Action:
    Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from disease’s such as Alzheimer’s .

    COA

    Items of Analysis Requirements Results
    Appearance Off-white to white powder Conforms
    Loss on drying ≤1.0% 0.6%
    Heavy metal ≤10ppm Conforms
    Water ≤0.5% 0.3%
    Purity(HPLC) ≥99% 99.47%
    Residue on ingnition ≤0.3% 0.05%
    Conclusion The product conforms to in House Standard
    Packing Pack in two layers plastic-bag.
    Storage Store in a well-closed place with constant low temperature and no direct sun light.
    Shelf life 2 years when properly stored.

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