Adrenosterone (Androst-4-ene-3,11,17-trione)

Androgenic Steroid Prohormone Adrenosterone (Androst-4-ene-3,11,17-trione)

Basic Details:

Product Name: Adrenosterone
Synonyms: Androst-4-ene-3,11,17-trione
CAS: 382-45-6
MF: C19H24O3
MW: 300.39
EINECS: 206-843-2
Melting point: 219-222 °C(lit.)
alpha: 300 º (c=1 in chloroform)
refractive index: 290 °(C=0.2, EtOH)
storage temp: Refrigerator
appearance: Off-White to Pale Yellow Solid​

Description:

Adrenosterone is a steroid hormone with weak androgenic effect first isolated in 1936 from the

adrenal cortex. Adrenosterone occurs in trace amounts in humans as well as most mammals and

in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone.

Adrenosterone has shown to be converted into 11-ketotestosterone in humans, which contributes

to adrenosterone’s androgenic effects.

Application:

Adrenosterone’s main action is it lowers cortisol levels. Cortisol is the main catabolic (muscle-

eating) hormone and it also promotes fat gain. Cortisol and testosterone also work in an inverse

relationship, so high cortisol levels lower testosterone. Adrenosterone acts as a competitive

inhibitor, preventing cortisone from attaching to the 11b-hydroxysteroid dehydrogenase type I

reductase. By competing at the receptor, it keeps cortisone from attaching and converting to

cortisol through the enzyme. Adrenosterone is found naturally in the body and is released by the

adrenal glands. The body uses it as a way to help regulate cortisol levels.

Adrenosterone is a non-aromatizing analogue , which causes dry lean gains and fat loss, along

with an increased sexual desire. Adrenosterone is well regarded for its ability to lower cortisol

levels. Used mainly as a recomposition agent and to promote fat loss. Adrenosterone is also a

good choice for individuals looking to stack one prohormone with another.

Although it can cause the same side effects as other prohormone, it is considered very mild in

this regard. A good choice for people looking to lose weight and experience minimal side effects.